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Hello, my absolutely lovely membrane peeps! Would you maybe, pretty-please, let me proudly steer you to a MINI-REVIEW I recently wrote? It’s on asymmetric membranes in general, and differential stress in particular—subjects that I am massively interested in right now! 1/26

Beautiful, powerful methods to quantified lipid flow in cells, demonstrating the importance of non-vesicular lipid transport. Congratulations to the team.

Some of us were asked by Cell about the future of mechanobiology. In all likelihood, 20 years from now we'll see we were all wrong. Any thoughts? What did we miss?🤔🔮👇authors.elsevier.com/a/1j8Ml_278y%7…

We used light to herd cell growth with jared toettcher lab! Optogenetics is pretty cool. Super fun collab. and exquisite data from Kevin Suh* and Richard Thornton*. Video: blue light pattern--> sheet of living tissue rearranges into creepy eye. See jared toettcher for🧵. biorxiv.org/content/10.110…

How do bacteria grow and move in large groups where cells appear adhered to each other but can move freely? Using capillary forces from thin layers of water! Check out our new preprint with Matt Black, Chenyi Fei, Ricard Alert Zenón and Ned Wingreen: biorxiv.org/content/10.110…

Impressively strong magnetic effect on fluorescence of engineered protein Opens up new avenues for magnetogentics

Today in Science Magazine we report how lipids specialize for life under the crushing pressures of the deep sea and what this means more broadly for the composition of cell membranes (1/n) science.org/doi/10.1126/sc…

Just posted the most biologically important photopharmacology story we've had in the last few years. Ditched the photoswitch design principles we used for the last 10 years, & started all over again. And now it will work in vivo. doi.org/10.1101/2024.0… 🧵1/n🧵

Interesting work by Jorg Grandl shows how Piezo1 shape affects nearby channels directly.

SNAP-tag2: faster and brighter protein labeling biorxiv.org/content/10.110…

Excited to share our new preprint! Exceptional work by postdoc @MikeLange identifies the first #LipidDroplet lipid quality control pathway! Droplet-localized FSP1 safeguards stored neutral lipids, blocking their peroxidation & #ferroptosis induction.🤩biorxiv.org/content/10.110…

We are thrilled to share this work linking specific human brain cell types to psychiatric and neurological disorders, out now in Nature Neuroscience rdcu.be/d6Tcy See below for an overview and thanks to the amazing Tayden Li, William Giardino, Deis Sero, and so many others!

Beyond excited to share my big St. Jude news! We’re going to build an amazing hub for imaging technology development and deployment - driven by St Jude’s mission to transform the way the world understands and treats pediatric catastrophic diseases. Imaging innovators come join us!

I found out this morning that my NIH NICHD News F31 fellowship to study the biomechanics of uterine fibroids was CANCELLED.

Excited to share our work out in Current Biology ! We find that SKAP's binding to microtubules *reduces* friction at the kinetochore-microtubule interface and increases attachment stability under force. Congrats to postdoc Miquel miquel rosas salvans and all authors! With Caleb Rux

In our new preprint, we study the physical aging of biochemically active condensates formed by an engineered Tau protein into disease-linked amyloid fibrils — and investigate whether small molecules can counteract this transition. Priya R. Banerjee biorxiv.org/content/10.110… 🧵1/3

Sound-sheet microscopy is born! Congratulations to Baptiste Heiles, lab members and collaborators at the Shapiro Lab (Caltech) and Gazzola Lab (NIN/KNAW) for this scientific achievement 🚀.

A new optical biosensor can probe the activities of native GPCRs in live cells, and, unlike typical sensors doesn’t interfere with downstream signaling and can be deployed in many cell types with only a single construct. scim.ag/4cno5L1 Science Signaling

NIH grant awards plummeted $2.3 billion under President Trump statnews.com/2025/04/24/tru…

🚨 Second preprint of the week! We uncover the multiscale dynamics of active viscoelastic buckling in epithelia. We harness these mechanical instabilities for synthetic morphogenesis. Led by Nimesh Chahare🙌. Theory by Marino Arroyo and team. biorxiv.org/content/10.110…