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Structural snapshots uncover a key phosphorylation motif in GPCRs driving β-arrestin activation dlvr.it/SqkWyB

Hello, Cell !!! Stay tuned !!! So proud of our fantastic team and amazing collaborators !!!

Ben Sabari Ben Sabari will speak in the "Transcription and Chromatin Regulation" session about selective partitioning of disorder-mediated condensates and their role in gene regulation. His lab studies the function of long terminal IDRs present on many transcriptional regulators.

Online now - the Scientific Life article "Dissecting the biophysics and biology of intrinsically disordered proteins" from Priya R. Banerjee Alex Holehouse Kriwacki Lab Paul Robustelli Hao Jiang Alexander Sobolevsky Hurley Lab and Joshua Mendell. authors.elsevier.com/a/1i2zM3S6GfMm…

My former PhD student Priyanka Dogra & I wrote a "New & Notable" piece on "Illuminating the interface: Protein aggregation at the condensate interface" in Biophysical Journal Biophysical Journal for a beautiful paper by Cliff Brangwynne & coworkers brangwynnelab. cell.com/biophysj/fullt…

NMR of glutamine-rich prion-like domains in a condensed phase - new stuff from Sandy Wang and Tongyin Zheng . Structure and position-specific interactions of prion-like domains in transcription factor Efg1 phase separation biorxiv.org/content/10.110…

Excited to announce 3rd Subhash Mukhopadhyay Symposium along with Maharshi Krishna Deb to be held at IISc Bangalore on 13th to 15th Jan 2024 supported by EMBO YIP focusing epigenetic inheritance, embryogenesis, stem cell and germ cell biology #EMBOSMS2024

Joint postdoc position available with Ashley Solmonson @ASolmonson at the interface of developmental metabolism and gene regulation. Please get in touch if interested!

A long sought after hypothesis has been that organizing biomolecules in and around nuclear bodies is essential for functional RNA processing. We now provide direct evidence of this in nature for nuclear speckles and mRNA splicing. Check out this thread! nature.com/articles/s4158…

Checkout the latest work from the lab online today in Molecular Cell where we find that distinct sequence features encoded in IDRs are responsible for targeting proteins to specific condensates. This work was led by Nancy De La Cruz Prashant Pradhan and Reshma T Veettil .

I also want to highlight a very nice Preview article written by Meg Palacio and TaatjesLab. cell.com/molecular-cell…