
Keith W Pratz MD
@pratzkw
Director of Leukemia, Hospital of University of Pennsylvania Philadelphia. #Pennmedicine, Alumni Mayo Clinic Rochester (IM’05), Johns Hopkins Hospital (Med Onc)
ID: 1455893929182760961
03-11-2021 13:45:42
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My pleasure to host rising starts in Penn Medicine - Abramson Cancer Center Heme/Onc Fellowship for journal club reviewing AGILE Ivo/aza manuscript!


Happy to share the LTFU data from VIALE-A Phase III trial for Newly diagnosed AML unfit for induction. With 43.2 months follow up median OS 14.7m with Venetoclax/Azacitidine. Details of dosing adjustments in patients on therapy >6 cycles included. onlinelibrary.wiley.com/doi/10.1002/aj…










Happy to share our report on the utility of post remission use of GCSF in the VIALE-A trial. In the CR/CRi patients given GCSF, OS was 30.8 m vs 21.1 mo and MRD neg response 51% vs 33%. Important data to feel safe to use GCSF w/ blast clearance. onlinelibrary.wiley.com/doi/10.1002/aj…






Search for novel strategies in TP53 AML reveals mevalonate pathway importance in chemoreststance. Congratulations to Sarah Skuli and team on this work!