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Thrilled to share new work led by Jie Yang in the lab published today in nature. We find that Aspirin prevents metastasis by releasing T cells from immune suppression by platelet TXA2. Cambridge University CRUK Cambridge Centre rdcu.be/eci1U

Greyson has been through so much & needs a miracle. Please Pray. 🙏🏻 💔 #ChildhoodCancer 💔

🔁PLEASE SHARE #LifeForLeo 🔁 “Our brave baby boy, Leo, is in urgent need of help. His only chance for survival is a stem cell transplant, and there are currently no suitable matches on any national or international registries. We’re pleading for your help.”

Five years ago our sweet Beans came into this world. Just nine months later she left it. She would have five, but she's forever nine months old to us. On her 5th birthday please consider a donation to help us fight childhood cancer. profile.pmc.org/AK0302

My name is Ashley. I was diagnosed w/ #BrainCancer when I was 11 & left Earth at 13. My Dad promised me before I died that he will continue to fight for me, help as many Children as he possibly can battling this terrible disease & founded Cancer Response Team

Registration is now open for the 7th online Mendelian randomisation course, which will be held May 15-16, 2025. More information and registration here: imperial.ac.uk/school-public-… Retweets are appreciated. James Yarmolinsky Ville Karhunen Verena Zuber Kostas Tsilidis Imperial School of Public Health

Accelerated preview of Mutograph paper on colorectal cancer published in nature today. Results suggest that increase in early onset colorectal cancer may be linked to childhood exposure to some types of E.Coli bacteria that produce genotoxin colibactin. nature.com/articles/s4158…

I am FREAKING OUT & NEED your Help. 🙏🏻 As you may know, I founded a #ChildhoodCancer Charity after my 13 year old Daughter died from brain cancer & honored to have helped hundreds of Children since. We are currently extremely low on funds & to continue our mission, we need

When I post about my Daughter, it's not to get sympathy. It’s to keep her memory alive. ❤️ Your Follow & Repost would mean so much to get our Voices heard in our #ChildhoodCancer community. Please help our Children fight cancer. 🙏🏻 I miss you, Ashley. #Forever13

My 13 year old Daughter died from #BrainCancer 5,504 days ago. 💔 I would LOVE to see my Ashley’s name 5,504 times in comments for all the days she’s been missing. When you lose a Child, the most beautiful word you can hear is their name. ❤️ A Repost & Follow would mean the

Excited to share our recent nature paper! nature.com/articles/s4158… Tremendous collaborative effort from UChicagoCancerCenter The University of Chicago University of Chicago Radiation Oncology Ralph Weichselbaum

New paper published at AJE Advances: "The role of estimation in Mendelian randomization: should Mendelian randomization investigations provide estimates?" led by Benji Woolf and myself. Brief thread:

My precious Ashley died from #BrainCancer at only 13. We are still a mighty team, working together & making a difference in our #ChildhoodCancer community. We would be so grateful for a follow to reach the public & keeping our Ashley’s story alive. 🩷 𝒜𝓈𝒽𝓁𝑒𝓎 🩷

My lab's first paper is out in nature. We show that lipoprotein uptake protects tumors from ferroptosis by delivering the lipid antioxidant α-tocopherol. Surprisingly, tumors use sulfated glycosaminoglycans—not canonical receptors—to capture lipoproteins. nature.com/articles/s4158…

The biggest promise of GWASs is the discovery of novel biology underlying human disease with the potential of detecting promising drug targets🧬-->💊 While GWASs have now delivered thousands of signals, moving from variants to causal genes is very challenging. 👇This

Why do some X accounts rack up hundreds of thousands of followers, yet #ChildhoodCancer accounts barely get noticed? 🤔

My Ashley didn’t deserve to die from #BrainCancer 💔 If I could somehow get the public’s attention & have them get a glimpse into this world, we’d have an army advocating for our #ChildhoodCancer Warriors. Your follow, repost & supporting Cancer Response Team (Cancer Response Team🎗)

Final version of nature paper on mutational signatures for colorectal cancer. nature.com/articles/s4158… Important implications for early onset colorectal cancer. Check out paper or video below. Thanks as always to Cancer Grand Challenges + team Wellcome Sanger Institute and Ludmil, Marcos UC San Diego

I wrote a little bit about a cool recent paper looking at heritability estimates from very large registry data, and how we still really don't understand why outcomes track in families. A short 🧵:

Happy Heavenly Birthday, Ashley. ❤️ She continues to be our guiding light, inspiring us to make a tangible difference in the lives of those affected by #ChildhoodCancer Every step we take, every family we support, is a testament to her bravery & the enduring legacy she has left