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Join us in advocating for #renewableantibody resources in basic and biomedical research. Sign the petition urging NIH to prioritize developing, funding, and implementing validation protocols. Let's establish guidelines for reproducibility and specificity! bit.ly/3NpLrDC

📢 We are #hiring medicinal chemistry #postdocs to develop chemical probes! This project is part of the Acceleration Consortium (AC)  ‘self-driving lab’s research to accelerate materials and #drugdiscovery assisted by #AI and automation. Find more⬇️ thesgc.org/careers/toront…

Nice to see some of our epigenetics chemical probes featured in this cool study! nature.com/articles/s4155…

Surprising to see how widespread effects these drugs have on the health system and the economy . reuters.com/breakingviews/…

sciencealert.com/toxic-tiny-rna…

Wow, these drugs keep giving! nature.com/articles/d4158…

This paper from the Lorenz lab uses 4 different Structural Genomics Consortium (SGC) #ChemicalProbes (among others) to ask questions about human neuronal development. Exactly the reason we made our probes openly available. So people can use them to do cool things! nature.com/articles/s4158…

A new study demonstrates for the first time the ability of Huntingtin protein to directly bind to RNA species. Read our preprint and learn more about the role of a specific RNA, called NEAT1, in connecting with Huntingtin within cells. 📰 biorxiv.org/content/10.110…

We finally know why humans don't have tails: a tail of transposable elements and splicing! livescience.com/health/genetic…

Want to learn about the kinases involved in ciliogenesis? Check out our review on the Illumination of understudied ciliary kinases frontiersin.org/articles/10.33…

Excited to share our new story on PRMT5 regulating Huntingtin(HTT) mRNA processing. We thought PRMT5 was regulating HTT splicing but it turned out to be intronic polyadenylation resulting in premature transcription termination of the HTT mRNA. I'll post a separate tweetorial.

Check this out if you want to find chemical probes or drugs targeting your pathway. From idea to a paper and an app in less than a year!

Majestic Temple of Afaia in Aegina! Cats are everywhere, even in ancient Temples!

Huntingtin is an RNA binding protein and participates in NEAT1-mediated paraspeckles pubmed.ncbi.nlm.nih.gov/39028820/ Awesome study by Manisha Yadav, Rachel Harding , Mahmoud A. Pouladi , hansenhe and Pearson Labs

Great public engagement initiative nature.com/articles/s4146…

🚨 Excited to share our new publication in Nature Communications on PRMT inhibition in kidney cancer! 🙌 Big thanks to @laillesuhnrese1, Structural Genomics Consortium (SGC), Cheryl Arrowsmith, Brian Raught, and the entire team!👏Read more here: nature.com/articles/s4146… #cancerresearch #kidneycancer #UHN

sciencealert.com/fda-approved-a…

World-first therapy using donor cells sends autoimmune diseases into remission go.nature.com/3XTDXOC

🔥NEW PAPER ALERT🔥: our study on perturbing CAF activation to modulate tumor invasion is out in @Biomaterials. If you like bioengineering, targeted screening and cell phenotype perturbations, this story is for you! 👀 (doi.org/10.1016/j.biom…

Every lab has had experience with bad antibodies. They are a big waste of time, money and lab resources and lead to false and irreproducible results. Initiatives such as the SGCs YCharOS help pinpoint the good ones and will save time, money and resources.