Actions for RheumaticFever & RheumaticHeartDisease 1. Strengthen primary & secondary prevention 2. Integrate RHD services into PrimaryHealthCare 3. Secure reliable supply of benzathine penicillin G 4. Ensure well-resourced & trained health workforce #WHA71 #GlobalHealth #GBDstudy

The CHIP you don't want annals.org/aim/article-ab… Annals of Int Med Succinct summary of what we know and don't know about "Clonal Hematopoiesis of Indeterminate Potential," a new risk factor for heart disease and pre-#cancer marker, common w/ aging

Read this provocative review of Vitamin D and its implications for #HeartDisease. It addresses the differences between our body’s own production of #VitaminD and what we ingest as pills or through diet. Conclusions may surprise you! #CVD #Risks circres.ahajournals.org/content/122/11…

Read! A bold new approach to rational drug development, testing, and treatment. Jane Leopold & Joe Loscalzo detail the importance of deep phenotyping & interactome networks. The figure shows current approach vs. #PrecisionMedicine approach. #HLBSpopOmics circres.ahajournals.org/content/122/9/…

On #WorldNoTobaccoDay, we support all who are trying to quit or recently quit #smoking. Tools, tips, and other resources are available at smokefree.gov. @NIH_NHLBI American Thoracic Society (ATS) American Heart Association

One single cell-level #epigenetics mechanism explaining why advancing age is such a powerful marker of #CardiovascularDisease and All-Cause #Mortality . #Aging #HLBSpopOmics #PHGKB cell.com/cell/fulltext/… … … x.com/EricTopol/stat… … x.com/EricTopol/stat…

Frameworks are emerging for integrating Social Determinants of Health (#SDoH) into #PrimaryCare. The 5 questions we need to ask and what we need to learn to make this a reality: bit.ly/2xjnk0s.

Important article highlights post-discharge vulnerability: 1 Sleep Disruption 2 Malnourishment 3 Mobility Restriction 4 Other Stressors 5 Allostatic Overload It also suggests interventions that might improve outcomes. journalofhospitalmedicine.com/jhospmed/artic… … x.com/PaulSaxMD/stat…

SUICIDE is more than a mental health condition: 1. Nearly 45,000 lives lost to #suicide in 2016. 2. Suicide rates up more than 30% in half of states since 1999. 3. More than half of people who died by suicide did not have a known #MentalHealth condition. go.usa.gov/xQmab

Applying genome sequencing in healthy individuals is often justified by its relatively low cost. But even if sequencing becomes truly inexpensive, substantial medical costs can result actions that their results trigger. Via JAMA. jamanetwork.com/journals/jama/…

Genetic risk scores look increasingly promising in clinical practice but empirical data will be needed to evaluate whether they can lead to behavior change. ncbi.nlm.nih.gov/pubmed/2978968… Cecile Janssens Sek Kathiresan MD Eric Topol Ali Torkamani x.com/minouye271/sta…

Enough said.

Rwanda’s health system has become a model for other nations to follow. The country’s example should inspire all leaders to renew their commitments to primary health care. #Astana2018

Persistent racial/ethnic and income disparities in genetic testing and targeted treatment in patients with metastatic lung cancer. Via #CEBP. cebp.aacrjournals.org/content/early/…

An astute perspective on physician burnout: the history, the drivers, and potential for a renaissance thelancet.com/journals/lance… The Lancet by Daniel Marchalik Georgetown Medicine

Overcoming the many challenges of rare genetic diseases. Terrific nature collection of articles. nature.com/collections/ef… #rarediseaseday2019

Diversity is good for innovation. This is a great conversation between Ayanna Howard and @timnitGebru (@dair-community.social/bsky.social) on the importance of representation and female leadership in tech. b-gat.es/2FhOpZ2

NHLBI 2019 Research Highlights: As 2019 nears its end, we're looking back on some newsworthy findings from NHLBI-funded research. For more 2019 news highlights, browse here: go.usa.gov/xp62b @NHLBI_HEARTDir @NHLBI_LUNGDir @NHLBI_BLOODDir @NHLBI_Translate @TheBethesdaLabs

The Global Burden of Disease keeps saying the same things...but we still don’t listen, says Graham MacGregor.