Dr. Fabian Proft (@proftdr) 's Twitter Profile
Dr. Fabian Proft

@proftdr

I have left twitter march 2025 because of the change under Musk and Trump administration

ID: 1264174070557478912

calendar_today23-05-2020 12:39:31

4,4K Tweet

1,1K Followers

645 Following

Giuseppe Lopalco (@giuseppelopalc2) 's Twitter Profile Photo

๐Ÿš€ Thrilled to share a new work with my friends Vincenzo Venerito & Dr. Fabian Proft ! ๐ŸŽ‰ We explore the evolution of #axSpA treatment, from early intervention with biologics and synthetic drugs to personalized strategies for optimal outcomes. ๐Ÿฉบ๐Ÿ”ฌ tandfonline.com/doi/full/10.10โ€ฆ

Annals of the Rheumatic Diseases (@eular_ard) 's Twitter Profile Photo

๐ŸŒŸ Exciting new recommendations for a standardized MRI protocol to evaluate SIJยดs! The ASAS SPARTAN collab introduces a 4-sequence standard to improve sacroiliitis diagnosis. ๐Ÿ”โœจ Check it out ๐Ÿ“š๐Ÿ”—: ard.bmj.com/content/early/โ€ฆ #MedicalImaging #MRI #axSpA

๐ŸŒŸ Exciting new recommendations for a standardized MRI protocol to evaluate SIJยดs! 
The <a href="/Official_ASAS/">ASAS</a> <a href="/SPARTAN_Updates/">SPARTAN</a> collab introduces a 4-sequence standard to improve sacroiliitis diagnosis. ๐Ÿ”โœจ 
Check it out ๐Ÿ“š๐Ÿ”—: ard.bmj.com/content/early/โ€ฆ  
#MedicalImaging #MRI #axSpA
Annals of the Rheumatic Diseases (@eular_ard) 's Twitter Profile Photo

๐ŸšจReview on RA Prevention by Cope et al.: Can we stop RA before it starts? ๐Ÿ”ฌ๐Ÿšซ โœ… Rituximab & Abatacept can delay RA onset โŒ Steroids & Statins showed no impact ๐ŸŽฏ Next-gen trials focus on precision-based prevention to stop RA in its tracks! ๐Ÿ”— ard.bmj.com/content/early/โ€ฆ

๐ŸšจReview on RA Prevention by Cope et al.:
Can we stop RA before it starts? ๐Ÿ”ฌ๐Ÿšซ

โœ… Rituximab  &amp; Abatacept can delay RA onset
โŒ Steroids &amp; Statins showed no impact
๐ŸŽฏ Next-gen trials focus on precision-based prevention to stop RA in its tracks!

๐Ÿ”—  ard.bmj.com/content/early/โ€ฆ
Annals of the Rheumatic Diseases (@eular_ard) 's Twitter Profile Photo

๐Ÿ’ก Exciting new research showcases the potential of CD19-CAR T-cell therapy in autoimmune diseases! It achieves complete B-cell depletion in deep tissues ๐ŸŒŸ๐Ÿ”ฌ , outperforming RTX Could this pave the way for long-term, drug-free remission? ๐Ÿ’Š๐Ÿงฌ ๐Ÿ”— bit.ly/4d7utou

๐Ÿ’ก Exciting new research showcases the potential of CD19-CAR T-cell therapy in autoimmune diseases! 

It achieves complete B-cell depletion in deep tissues ๐ŸŒŸ๐Ÿ”ฌ , outperforming RTX

Could this pave the way for long-term, drug-free remission? ๐Ÿ’Š๐Ÿงฌ 

๐Ÿ”— bit.ly/4d7utou
Annals of the Rheumatic Diseases (@eular_ard) 's Twitter Profile Photo

๐Ÿ”ฌ New study reveals Protein Kinase R (PKR) is highly expressed in dermatomyositis muscle and drives IFN-ฮฒ-induced muscle damage ๐Ÿ’ฅ๐Ÿงฌ. Inhibiting PKR could be a promising therapeutic target to reduce muscle damage in DM patients! ๐Ÿ’ชโœจ ๐Ÿ”— Read more: bit.ly/4e05Kn3

๐Ÿ”ฌ New study reveals Protein Kinase R (PKR) is highly expressed in dermatomyositis muscle and drives IFN-ฮฒ-induced muscle damage ๐Ÿ’ฅ๐Ÿงฌ. 
Inhibiting PKR could be a promising therapeutic target to reduce muscle damage in DM patients! ๐Ÿ’ชโœจ 

๐Ÿ”— Read more: bit.ly/4e05Kn3
GRAPPA Network - Official (@grappao) 's Twitter Profile Photo

Join us a week from tomorrow for an exciting recap of the latest research and key updates in psoriatic disease abstracts presented at EADV. Donโ€™t miss the chance to dive into insightful discussions and cutting-edge advancements in the field. ๐Ÿ”— Register today and be part of this

Join us a week from tomorrow for an exciting recap of the latest research and key updates in psoriatic disease abstracts presented at EADV. Donโ€™t miss the chance to dive into insightful discussions and cutting-edge advancements in the field.

๐Ÿ”— Register today and be part of this
Annals of the Rheumatic Diseases (@eular_ard) 's Twitter Profile Photo

๐ŸงชExciting Phase 1 Study Results on OA!โœจ ๐Ÿ”น GSK3858279, a first anti-CCL17 mAb, shows promising efficacy in treating knee pain in OA! ๐Ÿ”น Results from an RCT: โœ”๏ธ Reduced pain intensity ๐Ÿ“‰ โœ”๏ธ Improved function๐Ÿ‹๏ธโ€โ™‚๏ธ โœ”๏ธ Favorable safety & tolerability ๐Ÿ’‰ ard.bmj.com/content/early/โ€ฆ

๐ŸงชExciting Phase 1 Study Results on OA!โœจ

๐Ÿ”น GSK3858279, a first anti-CCL17 mAb, shows promising efficacy in treating knee pain in OA!

๐Ÿ”น Results from an RCT:
โœ”๏ธ Reduced pain intensity ๐Ÿ“‰ 
โœ”๏ธ Improved function๐Ÿ‹๏ธโ€โ™‚๏ธ 
โœ”๏ธ Favorable safety &amp; tolerability ๐Ÿ’‰ 

ard.bmj.com/content/early/โ€ฆ
Annals of the Rheumatic Diseases (@eular_ard) 's Twitter Profile Photo

๐Ÿ”ฌ Exciting findings in #LupusNephritis! ๐Ÿบ ๐ŸŒŸ Potent B cell response linked to activated granzyme K+ CD8 T cells ๐Ÿ”ฅ in the kidney with cutting-edge techniques used! ๐Ÿงฌ๐Ÿงช ๐Ÿ‘‰This immune interaction could lead to innovative treatments๐Ÿ’Š ๐Ÿ”— bit.ly/3A7kodH

๐Ÿ”ฌ Exciting findings in #LupusNephritis! ๐Ÿบ 

๐ŸŒŸ Potent B cell response linked to activated granzyme K+ CD8 T cells ๐Ÿ”ฅ in the kidney with cutting-edge techniques used! ๐Ÿงฌ๐Ÿงช

๐Ÿ‘‰This immune interaction could lead to innovative treatments๐Ÿ’Š
๐Ÿ”— bit.ly/3A7kodH
Annals of the Rheumatic Diseases (@eular_ard) 's Twitter Profile Photo

๐Ÿšจ New trial results! ๐Ÿ’Š ๐Ÿ’‰ IFX & ADA show efficacy in treating severe mucocutaneous Behรงetโ€™s syndrome๐ŸŒŸ๐Ÿ’ฅ Both anti-TNFiยดs improved symptoms & QoL significantly over 6 months ๐Ÿ”ฅ โœ… 94% ADA response โœ… 64% IFX response โœ… Safe & effective! ๐Ÿ”— ard.bmj.com/content/early/โ€ฆ

๐Ÿšจ New trial results! ๐Ÿ’Š 

๐Ÿ’‰ IFX &amp; ADA show efficacy in treating severe mucocutaneous Behรงetโ€™s syndrome๐ŸŒŸ๐Ÿ’ฅ
Both anti-TNFiยดs improved symptoms &amp; QoL significantly over 6 months ๐Ÿ”ฅ

โœ… 94% ADA response
โœ… 64% IFX response
โœ… Safe &amp; effective!

๐Ÿ”—  ard.bmj.com/content/early/โ€ฆ
Annals of the Rheumatic Diseases (@eular_ard) 's Twitter Profile Photo

๐Ÿ”ฌStratification by autoantibodies in SSc reveals unique molecular signatures ๐Ÿงฌ๐ŸŒŸ SCL70+ pts show a pro-inflammatory, fibrotic profile ๐Ÿ”ฅ, while ACA+ pts exhibit immunomodulation & tissue homeostasis ๐Ÿ›ก๏ธ. A guide for tailored treatments strategies? ๐Ÿ’ก ๐Ÿ”—ard.bmj.com/content/early/โ€ฆ

๐Ÿ”ฌStratification by autoantibodies in SSc reveals unique molecular signatures ๐Ÿงฌ๐ŸŒŸ 
SCL70+ pts show a pro-inflammatory, fibrotic profile ๐Ÿ”ฅ, while ACA+ pts exhibit immunomodulation &amp; tissue homeostasis ๐Ÿ›ก๏ธ.

A guide for tailored treatments strategies? ๐Ÿ’ก

๐Ÿ”—ard.bmj.com/content/early/โ€ฆ
Annals of the Rheumatic Diseases (@eular_ard) 's Twitter Profile Photo

Want to dive into experts perspectives on microbiome research in autoimmune diseases? ๐Ÿ’ฉ๐ŸŒŸ This viewpoint highlights current developments on the microbiome in RA, SLE & SpA ๐Ÿ”๐Ÿ’ก A field for microbiome-based therapies & personalized medicine? ๐ŸŒฑ๐Ÿ’Š๐ŸŽฏ ๐Ÿ”— ard.bmj.com/content/early/โ€ฆ

Annals of the Rheumatic Diseases (@eular_ard) 's Twitter Profile Photo

๐ŸŽฅ ๐Ÿ”ฌ Fascinating study using Imaging Mass Cytometry reveals 13 unique fibroblast subpopulations in SSc skin! ๐Ÿงซ๐ŸŒŸ Certain fibroblast types are linked to severe vs. mild skin fibrosis, highlighting potential targets for personalized therapies! ๐ŸŽฏ๐Ÿ’‰ ๐Ÿ‘‰ ard.bmj.com/content/early/โ€ฆ

๐ŸŽฅ ๐Ÿ”ฌ Fascinating study using Imaging Mass Cytometry reveals 13 unique fibroblast subpopulations in SSc skin! ๐Ÿงซ๐ŸŒŸ 

Certain fibroblast types are linked to severe vs. mild skin fibrosis, highlighting potential targets for personalized therapies! ๐ŸŽฏ๐Ÿ’‰

๐Ÿ‘‰ ard.bmj.com/content/early/โ€ฆ
GRAPPA Network - Official (@grappao) 's Twitter Profile Photo

๐ŸŽ™๏ธNew episode out wherever you listen to your podcasts: "Managing MSK Symptoms in PsO Patients: Who Should be in the Driver Seat?" A hot debate taken from the 2024 GRAPPA Annual Meeting, this episode of Inside GRAPPA is moderated by Dr. Mio Nakamura and features Dr. Laura