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Very excited to advance and improve on our STING inhibitors working with a great team UMass Chan Medical School Paul Thompson UMass Chan Biochemistry & Molecular Biotechnology UMass Chan Program in Innate Immunity

#newscience alert! We're working to take the STING out of diseases like #ALS, #lupus, & #SAVI. A new publication from Paul Thompson Kate Fitzgerald describes a promising new #STING inhibitor that could change the game for these diseases. #advancingtogether umassmed.edu/bmb/news-and-e…

cool paper from @doc_jlmeier Comparative Analysis of Drug-like EP300/CREBBP Acetyltransferase Inhibitors | ACS Chemical Biology pubs.acs.org/doi/10.1021/ac…

Please RT and tell your biochemistry/molecular biology/chemical biology/neurobiology/neurochemistry postdocs to apply! We will also welcome applications from established investigators who are looking for a new opportunity. ⤵️⤵️⤵️

Citrullination is a chemical protein modification, which has gained great interest because it is associated with #autoimmunity, #neurodegeneration and #cancer progression. Read the new #PhilTransB issue, edited by Maria Christophorou, Priyanka Sharma & Xuesen Zhang: bit.ly/PTB1890

The product of a wonderful 2-day conference on citrullination last year in Nottingham. Please reach out if interested in copies of our manuscripts on #aging and #Staphylococcus aureus #sepsis in this issue

🕸️👀 Inhibition of neutrophil extracellular trap formation alleviates vascular dysfunction in type 1 diabetic mice science.org/doi/full/10.11…

#AtlasRetreat2023 ⁦Bruce Booth⁩’s Year In Review is sobering. Interesting to see small molecules (“smiracles”?) still dominating deal appetite.

intriguing study further linking PAD6 to infertility. New explanation for infertility: eggs lacking a mysterious ‘lattice’ nature.com/articles/d4158…

Are you interested in graduate school? Then check out all the new research groups and the entire Department of Chemistry and Biochemistry at the University of South Carolina. Grad applications are FREE this year! eee5j46l83.postedstuff.com/V2-w8VF-DUFb-s…

Excited to share our latest article published in @plospathogens: journals.plos.org/plospathogens/… #plospathogensauthor #citrullination #PTM #herpes #HSV Università di Torino UPO - Università NoToVir Paul Thompson VIPLab

Super cool new paper from the Weerapana lab!!! Profiling nuclear cysteine ligandability and effects on nuclear localization using proximity labeling-coupled chemoproteomics: Cell Chemical Biology cell.com/cell-chemical-…

Very happy to be able to share this preprint from a fab collaboration with Maria Christophorou. It's been a long journey to get here but we hope you'll agree with us that it was worth it. Just a preprint at the moment so any thoughts or suggestions very welcome!

#newscience alert! BIG UPDATE! INCREASED PROTEIN CITRULLINATION IN MOUSE MODELS OF ALS ARE ALSO SEEN IN HUMAN ALS BRAIN SAMPLES!!! @lyleostrow @pthompsn1018 pubmed.ncbi.nlm.nih.gov/38253209/

BRIDGE Fund UMass Chan Medical School commits $2 million to take faculty research from the bench to the bedside: direc.to/kEXw Sharon B. Cantor Molecular, Cell and Cancer Biology RNA Therapeutics Institute Paul Thompson UMass Chan Biochemistry & Molecular Biotechnology Marcus Ruscetti Lab

Wow. Investors in Padlock Therapeutics sue Bristol Myers Squibb over ‘milestone’ payments The plaintiffs allege the pharma giant reneged on part of an acquisition agreement. Michael Gilman statnews.com/2024/12/12/pad…