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The importance of molecular layer interneurons in ataxia

Actually the cliche “endangered species” was used in 1979! Sometimes it is worth referencing old sources—nothing really new under the sun

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Spinocerebellar ataxia type 4 is caused by a GGC expansion in the ZFHX3 gene and is associated with prominent dysautonomia and motor neuron signs | medRxiv. The first polyglycine disorder.⁦National Ataxia Foundation⁩ medrxiv.org/content/10.110…

The Ataxia Global Conference 2023 (15-16 November) was a great success! We are grateful to all collaborators and all attendees for excellent talks and discussions. 🩷🩷🩷👩‍💻👨‍🔬👨‍🦽👩‍⚕️🧍‍♀️🩷🩷🩷 National Ataxia Foundation Ataxia UK FA Research Alliance Ataxia Centre - UCL Institute of Neurology Ataxia and Me CIO 1184030 Critical Path Institute (C-Path)

#Editor's note by ASCI member Puneet Opal in Journal of Clinical Investigation : Mutations in the cytoplasmic iron-sulfur assembly protein CIAO1 cause neuromuscular deficits: buff.ly/3xqQJuE Related article: buff.ly/3KTfUt4

Our group is expanding! Northwestern #postdocjobs #neurodegeneration . Looking broadly for smart and curious scientists. Spread the word! jobrxiv.org/job/northweste…

We are hiring! Looking for computational skills to address neurodegeneration #computationalbiology #datascientist Please spread the word! jobrxiv.org/job/northweste…

Postdoc/Research Scientist Puneet Opal Come join our # neurodegeneration team as a #postdoc in #Chicago jobrxiv.org/job/northweste… #age_related_disease #animal_models #basic_science #cell_biology #neurodegeneration #ScienceJobs #job jobrxiv.org/job/northweste…

Computational/Data Scientist Puneet Opal Come and join our #bioinformatics team at #Chicago studying #neurodegeneration jobrxiv.org/job/northweste… #animal_models #big_sequence_data_DNA #bioinformatics #computational_biology #neurodegeneration #ScienceJo... jobrxiv.org/job/northweste…

Postdoc/Research Scientist Puneet Opal Come join our # neurodegeneration team as a #postdoc in #Chicago jobrxiv.org/job/northweste… #age_related_disease #animal_models #basic_science #cell_biology #neurodegeneration #ScienceJobs #job jobrxiv.org/job/northweste…

Join course directors Puneet Opal, MD, and Tanya Simuni, MD, for the "Update on the Diagnosis and Management of Movement Disorders" meeting on November 2. This program will provide the latest advances in the field of neurodegenerative disease related to diagnosis, treatment and

We’re excited to announce the Denning Ataxia Center at Northwestern Medicine, a hub dedicated to improving the understanding of #ataxia through research with patient-centered clinical care. This new center will be led by Puneet Opal, MD. Learn more about how this center will strive to

Bridging the gap: Insights into sensory-motor deficits in NMDA receptor antibody encephalitis: jci.org/articles/view/… Puneet Opal & Geoffrey T. Swanson Northwestern Feinberg School of Medicine comments on Zhou et al. (jci.org/articles/view/…)

.NM Neurology Northwestern Feinberg School of Medicine

Understanding How Neurofilaments Clog Up Brain Functions - News Center. ⁦Northwestern Feinberg School of Medicine⁩ ⁦NM Neurology⁩ ⁦NUIN⁩ news.feinberg.northwestern.edu/2025/03/11/und…

ASCI member Puneet Opal et al. Northwestern Feinberg School of Medicine show that neurofilaments accumulate and dually disrupt the process of autophagy in neurons when gigaxonin function is compromised-- contributing to the pathogenesis of other neurodegenerative diseases with neurofilament accumulations.

Thank you National Ataxia Foundation CRCSCA investigators and ataxia leaders Sheng-Han Kuo, MD Schmahmann Lab Puneet Opal for making this work possible! ✅Suicidal thoughts in SCA is 3x higher than general population, and early suicidal thoughts = 59x higher risk later pubmed.ncbi.nlm.nih.gov/40350965/

Clinical Reasoning: A 57-Year-Old Man With Chronic Gait Unsteadiness and Diminished Lower Extremity Sensation Neurology Journal neurology.org/doi/pdf/10.121…

Puneet Opal NM Neurology