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Brain hemodynamic signals show 1/f-like dynamics, but how does this relate to neural activity? Qingguang Zhang &co reveal that 1/f-like dynamics in brain oxygenation reflect the heterogeneity of red blood cells, not neuronal activity #PLOSBiology plos.io/2Ui6h03

Check out our recent work: a how-to guide for monitoring and analyzing brain activity~

Join us for this exciting project~

This special issue is becoming a wonderful collection of reviews and protocols for cerebrovascular enthusiasts. Contributions from experts on #pericytes, #endothelium, #astrocytes, #fibroblasts, #ImmuneCells, #BrainClearance and advanced optical imaging! spiedigitallibrary.org/imaging-neuroi…

#JNeurosci: Using high-resolution 3D mapping methods in adult mice, Son et al. yongsookimlab Penn State found Oxytocin connections with 9 functional brain circuits controlling cognition, brain state, & somatic visceral response. jneurosci.org/lookup/DOI/10.…

Our neurovascular mapping paper Cell Reports shows striking correlation between vascular network/pericyte and cortical neuronal cell types in mice. doi.org/10.1016/j.celr…. Congrats Yuan Ting Wu Hannah Bennett Qingguang Zhang drew_lab

Beyond its direct metabolic role, oxygen may function in a modulatory fashion in the brain. Check out our drew_lab review of this speculative hypothesis in Pflugers Archiv - European Journal of Physiology. doi.org/10.1007/s00424…

New research from yongsookimlab explores how different regions of the brain are supplied by energy via blood. Read more about their innovative mapping of vascular networks: bit.ly/3IpWkm2

Let's start the #lung week with a #review about the modulation of neural activity by respiration-driven blood #oxygen changes Qingguang Zhang drew_lab #brain rdcu.be/cRrrZ

Assistant Professor of Biology and of Biomedical Engineering @nicoleacrowley, has been awarded a five-year, $1.6 million grant from NIAAA News, part of NIH, to study the neurobiology of binge alcohol drinking. BBRFoundation Penn State Eberly College of Science Read more below: psu.edu/news/research/…

If the #Neurovascular unit were a solar system, the Neurovasculome would be the galaxy. This Statement in Stroke AHA/ASA explores the #Neurovasculome, and recent efforts to chart the diversity of vascular structures and functions that support brain health. ahajournals.org/doi/abs/10.116…

We team up with drew_lab to examine anatomical and functional changes in aged mouse brain. We found that aging induces selective regional vascular and pericyte degeneration, slowed NVC response, and lower oxygen carrying capacity. biorxiv.org/content/10.110…

drew_lab, Kevin Turner, Nanyin Zhang, Qingguang Zhang show that sleep-related vascular changes dominate over sensory-evoked changes with a combination of optical imaging, electrophysiology, and BOLD fMRI in unanesthetized neonatal mice. nature.com/articles/s4200…

Interested in using optical imaging method to study brain blood flow regulation? Our lab have two positions open: Lab technician: careers.msu.edu/en-us/job/5180… Postdoctoral research associate: careers.msu.edu/en-us/job/5180…

Vascular simulation groups, we published simulation ready vascular map in the whole adult mouse brain (Wu et al., 2022 Cell Reports). We found a few glitches with the dataset. Here is the updated one with fixes. data.mendeley.com/datasets/mjtyr…

Aging vessel mapping paper is officially out. nature.com/articles/s4146… We examined structural and functional changes of cerebrovasculature and found brain region specific changes in normally aging C57 mice compared to young mice.

Test, test, it works~First two-photon imaging session in the book~