🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Happy to share our lab’s latest work in collaboration with Tahirov lab about the structures of human Polα-Primase DNA elongation complexes NatureStructMolBiol rdcu.be/c96yY. Congrats to all authors 🎉Thanks for all support from my PI Ci Ji Lim, Benjamin Lusk and collaborators! 🥳

Congratulations to Qixiang He 贺琦翔 and the rest of the rising stars of the inaugural class of Weill Institute Emerging Scholars!!! We are excited for Qixiang to share his latest research work with the Weill Institute for Cell & Molecular Biology research community in Oct. 🚀 UW–Madison Biochem UW-Madison Biophysics

Congratulations to all awardees!🎉 Thank you Weill Institute for Cell & Molecular Biology for providing the opportunity to share our research! Looking forward to it this Fall🥳

Happy to share our review of the human telomere C-strand fill-in mechanism. Appreciate the opportunity to be involved in the process and learn a lot from Ci Ji Lim and the revision. authors.elsevier.com/a/1hb3t3S6GfMl…

Our biggest discovery yet (IMO). The 5’ ends of our chromosomes are capped(!) by #telomeric protein POT1 to prevent their misrecognition as broken DNA. Brilliant work of Drs. Valerie Tesmer and Kirsten Brenner Science Magazine science.org/doi/10.1126/sc… 1/n

Online now - the Review "Models for human telomere C-strand fill-in by CST–Polα-primase" from Qixiang He 贺琦翔 and Ci Ji Lim. #telomeremaintenance #CStrandFillIn #CST #DNAsynthesis #primersynthesis Read it here 👉 authors.elsevier.com/a/1hb3t3S6GfMl…

Our first paper is out in Cell! Led by Rohith Rajasekaran, we present a programmable reaction-diffusion system that generates synthetic protein waves, oscillations, and patterns for spatiotemporal circuit design and FM data-encoding in human cells. authors.elsevier.com/a/1iN8ZL7PXmeeN

37 scientists will join the 2024 class of The Pew Trusts scholars and fellows, and we are proud to announce Professor Ci Ji Lim (Ci Ji Lim) is one of them! biochem.wisc.edu/2024/06/18/tel…

Congratulations to Qixiang He (Qixiang He 贺琦翔), who was awarded a Louis and Elsa Thomsen Wisconsin Distinguished Graduate Fellowship! biochem.wisc.edu/2024/07/12/qix… Ci Ji Lim UW–Madison CALS UW-Madison Biophysics

Huge congratulations to Qixiang for winning the highest recognition for graduate students. 🎉🚀 Thank you, Renata for writing up this award! 🙏🏻

Excited to receive the fellowship from UW–Madison CALS! Grateful for the support from Ci Ji Lim, UW–Madison Biochem and UW-Madison Biophysics!😁🙏

I'm thrilled to share my first project in Scott Coyle 🤩we found that MTs-assembly can be tuned at both MTBD and condensates. This project highlights my past(microtubule), present(SynBio), and future(LLPS): doi.org/10.1016/j.jbc.…

1/7 Our latest preprint is out! 🚨 Sourav Agrawal | ସୌରଭ , Xiuhua Lin , Vivek Susvirkar et al. discover human RPA is a critical telomerase processivity factor essential for telomere maintenance. This reshapes our understanding of human telomerase regulation. biorxiv.org/content/10.110…

My favourite discovery ever has just come online. Can I please tell you about some seriously wacky molecular biology? The story starts with a reverse transcriptase that SOMEHOW defends bacteria from viruses. (👇 I recommend sound ON for the video 🎹) 1/

1/8 ❄️🔬Excited to share our latest work published in Nature Communications! Led by Kaitlyn Abe and in colab with Tim Grant, we've discovered a simple, cost-effective way to mitigate sample damage at the air-water interface during grid preparation. #CryoEM rdcu.be/dSWfn

Congratulations to Zhijian “James” Chen, 2024 #LaskerAward winner! – “for the discovery of the cGAS enzyme that senses foreign and self DNA, solving the mystery of how DNA stimulates immune and inflammatory responses.” laskerfoundation.org/winners/cgas-e… #Lasker2024 #LaskerLaureate

Great #cryoET #cryoFIB #sub-tomo workshop ⁦⁦UW–Madison Biochem⁩ #cryoEM centers! New #teamtomo trainees ready, set, go! Thanks speakers, trainers, staff, sponsors. ⁦NIH Common Fund⁩ #cryoEM ⁦Delmic⁩ ⁦SubAngstrom⁩ Leica Microsystems⁩ ⁦Microscopy & Spectroscopy⁩

Curious about FM transmission of biological data? Check out our new preprint: "Genetically encoded protein oscillators for FM streaming of single-cell data." A game-changing toolkit to create cellular radios that communicate directly with cell biology. biorxiv.org/content/10.110…

The sequel to our DRT2 story is here, and this one is once again full of surprises! This time around, the Sternberg Lab teamed up with the Wiedenheft Lab to study how DRT9 reverse transcriptases provide antiviral immunity. Here’s what we found: biorxiv.org/content/10.110…

New pre-print(s) from the Sternberg Lab in collaboration with Leifu Chang! We uncover an unprecedented molecular mechanism of CRISPR-Cas12f-like proteins, which drive RNA-guided transcription independently of canonical promoter motifs. Full story here: tinyurl.com/mr3fd493