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Hello Dr Dronca from Mayo Clinic Rochester. Happy to join in today! #abcdrbchat

Hi Roxana Dronca from Mayo Clinic Rochester. Happy to join in today! #cimchat

Q2 Tumors have mechanisms to inhibit effective recognition by immune cells #cimchat

Q2 CI seek to overcome this inhibitory mechanisms #cimchat

RT Mayo Clinic Comprehensive Cancer Center 2 great videos from Mayo Clinic explain immunotherapy & how it works: mayocl.in/1pD9no6 #cimchat

Q3 Tumors such as #melanoma and #renal cell cancer have shown responses with CI but more are studied and show promise #cimchat

A3 Exciting results in #lungcancer for instance and promise in #bladder cancer #cimchat

A4 Studies have shown that combinations could work but we need to understand how to best time them #cimchat

RT Larry Pease, Ph.D. A4 Immunotherapy should be in administered in the context of comprehensive care #cimchat

Q5 Responses to #immunotherapies seem to be much more lasting than to #chemotherapy or to targeted agents #cimchat

RT Sharon Theimer Patients interested in Mayo Clinic trials can find them here; enter immunotherapy: mayo.edu/research/clini… #cimchat

Q6 Agents such as anti-PD1 and anti-CTLA4 are injections usually every 2-3 weeks; others such vaccines in #prostate ca are cells #cimchat

Q6 Nowadays we think about stopping once the patient has a good response, may not need maintenance #cimchat

RT Dr. S. Markovic A7: Possible if common tumor escape mechanisms are at play. #CIMchat

Q8 Yes this may be a new treatment option for many #cancers, patients should ask if it is appropriate for them #cimchat

Thank you everyone! Great chat #cimchat