RENOVATE (@renovatetrial) 's Twitter Profile
RENOVATE

@renovatetrial

#RENOVATE: Adaptive trial investigating the efficacy of #HFNC vs #NIPPV for #ARF. Funding: Brazilian Ministry Health, coordenated by #IPHCOR; NCT 03643939

ID: 1143200028527382528

calendar_today24-06-2019 16:51:41

152 Tweet

141 Followers

73 Following

Danny McAuley (@dfmcauley) 's Twitter Profile Photo

RENOVATE israel maia Leticia Kawano-Dourado (I'm on BlueSky/LinkedIn) Berry Consultants @RogerJLewis Otavio Ranzani Ellen Gorman Paul Dark Wow. What an amazing achievement. This is such an important trial to inform the place of non-invasive respiratory support in ARF. Hopefully another live stream at the best critical care meeting in the world Critical Care Reviews

Leticia Kawano-Dourado (I'm on BlueSky/LinkedIn) (@leticiakawano) 's Twitter Profile Photo

Critical Care research network part of the #RENOVATEtrial came to Sao Paulo today to discuss strategies to enhance recruitment, crossover avoidance ❌ from HFNC 🔁 NIVPP, and in-person networking 🤩 RENOVATE israel maia

Critical Care research network part of the #RENOVATEtrial came to Sao Paulo today to discuss strategies to enhance recruitment, crossover avoidance ❌ from HFNC 🔁 NIVPP, and in-person networking 🤩

<a href="/RENOVATEtrial/">RENOVATE</a> <a href="/israelmaia16/">israel maia</a>
Ellen Gorman (@ea_gorman) 's Twitter Profile Photo

A recent editorial in JAMA JAMA Network highlighted an individual patient data network meta-analysis would help clinicians decide which non-invasive respiratory support strategy is most effective in COVID-19. An IPDNMA is now registered crd.york.ac.uk/prospero/displ…

Leticia Kawano-Dourado (I'm on BlueSky/LinkedIn) (@leticiakawano) 's Twitter Profile Photo

I make Claudia's words my words And kudos to Ellen Gorman for pushing this challenging project forward! Love to see research teams collaborating: that is how science moves the fastest :-) israel maia RENOVATE

RENOVATE (@renovatetrial) 's Twitter Profile Photo

#RENOVATEtrial has recruited 1,456 patients🎉 Based on trial simulations, RENOVATE is coming closer to the sample size where a conclusion may be reached (superiority, non-inferiority, futility) Stay tuned! RENOVATE is an adaptive RCT led by israel maia & Leticia Kawano-Dourado (I'm on BlueSky/LinkedIn)

israel maia (@israelmaia16) 's Twitter Profile Photo

RENOVATE Proud to be part of this amazing team which has worked so well with many unexpected pandemic circumstaces these last 4 years to guarantee quality to maintain the study on track. #HCOR #PROADI #Brazilian Ministry of Health

Leticia Kawano-Dourado (I'm on BlueSky/LinkedIn) (@leticiakawano) 's Twitter Profile Photo

Jacobo Sellares Enric Barbeta Viñas Danny McAuley bronwen connolly Ellen Gorman israel maia Bram Rochwerg Claudia Crimi Additional question relates to the comparative effectiveness of the HFNC and NIV. Should one be preferred over the other for hypoxemic acute resp failure? That is one of the research questions of the RENOVATE (ongoing) Stay tuned

Leticia Kawano-Dourado (I'm on BlueSky/LinkedIn) (@leticiakawano) 's Twitter Profile Photo

1/ 🚨 Publication alert at Critical Care & Resuscitation Journal: Blinded update in the statistical analysis of the RENOVATE due to extraneous circumstances (#COVID19) not anticipated at the time of trial design sciencedirect.com/science/articl… Reasons for the update +

1/ 🚨 Publication alert at <a href="/CCRJournal/">Critical Care & Resuscitation Journal</a>:
Blinded update in the statistical analysis of the <a href="/RENOVATEtrial/">RENOVATE</a> due to extraneous circumstances (#COVID19) not anticipated at the time of trial design
 
sciencedirect.com/science/articl…

Reasons for the update +
RENOVATE (@renovatetrial) 's Twitter Profile Photo

#RENOVATEtrial reached an important milestone: 1,750 pts recruited 💥 triggering the last pre-planned interim analysis of the study! Huge thanks to pts & families, recruiting centers, #Hcor team, Berry Consultants, and our funder, the 🇧🇷 Ministry of Health (PROADI-SUS)

#RENOVATEtrial reached an important milestone: 1,750 pts recruited 💥 triggering the last pre-planned interim analysis of the study!

Huge thanks to pts &amp; families, recruiting centers, #Hcor team, <a href="/BerryConsultant/">Berry Consultants</a>, and our funder, the 🇧🇷 Ministry of Health (PROADI-SUS)
RENOVATE (@renovatetrial) 's Twitter Profile Photo

The RENOVATE trial has wrapped up the 90-day follow-up for its final patient (LPLV). 💥In these couple of months, we've been working on data collection for completeness & data cleaning, followed by ➡️ database lock 🔒 & analysis! Stay tuned! israel maia Leticia Kawano-Dourado (I'm on BlueSky/LinkedIn)