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In the latest issue! Hallmarks of neurodegenerative diseases dlvr.it/SjfpSz

Ruth Dreifuss: « Le féminisme est la plus grande révolution pacifique du XXème siècle. C'est aussi celle qui a apporté les plus grands changements » Brillante politicienne suisse. Merci rts.ch/info/suisse/13…

Our review on the role of TDP-43 and FUS in local translation for the maintenance of axons and neuromuscular junctions in health and ALS is now ONLINE!! authors.elsevier.com/c/1goF23BtfH5L… Tessa Robberechts & Sandrine Da Cruz

Thanks to Rickie Patani, @patanilab, @gavinpaulkelly, Jack Humphrey, @CarlosEcolEvol, Nicholas McGranahan, Raphaëlle Luisier, Nobby Chakrabarti, The Boulton Lab. Thanks to funders The Francis Crick Institute Medical Research Council NIHR UCLH Biomedical Research Centre. Most importantly thanks to the patients and families (12/12)

Une oncologue genevoise décroche une bourse d'un million de francs pour ses recherches Bravo! rts.ch/info/sciences-…

Collaborative NCCR PhD Fellowships for 3 Associate PIs: Pei-Hsuan (Xuan) Wu (UNIGE_en ) w/ Raphaëlle Luisier (Idiap Research Institute) Karsten Weis Lab (ETH Zurich ) w/ Leidel lab (Universität Bern ) Roger Geiger Lab (USI University ) w/ Prof. Dr. Steve Pascolo (Unispital_USZ) & Gerald Schwank (University of Zurich, not-NCCR ) bit.ly/3pJ749P

The AI program allows people with limited writing skills to create higher-quality texts — but makes little difference to proficient writers’ work quality. go.nature.com/3NZ0YuC

Nice interview George Cresswell!

Preprint by the Allain lab (ETH Zurich)&collaborators w/ first author Leonidas Emmanouilidis (Ble Vedouinos)"A solid beta-sheet structure is formed at the surface of #FUS liquid #droplets during aging"bioRxiv bit.ly/3slT33l #ALS #protein #nmrchat #rna Thomas Michaels

How to generate local mechanical forces to guide organoid patterning? Magnetoids 🧲! Actuate only a few cells within an organoid > bilateral domains in neural tube organoids Led by Abdel Rahman Abdel Fattah, 🧵: x.com/AR_AbdelFattah… 🔗: nature.com/articles/s4146…

#scRNAseq is a multimodal assay producing two count matrices: unspliced & spliced counts (e.g. for RNA velocity). Which should be used for clustering? Can they be used together? If so, how? Tara Chari w/ Gennady Gorin answer some of these questions in biorxiv.org/content/10.110… 1/🧵

Utilizing rare human brain biopsies we address: 1) Which cell types likely make amyloid? 2) How do microglia respond to amyloid and how does this compare to states in mouse models? 3) What neuronal states precede cell death in AD? Paper out today! cell.com/cell/fulltext/…

Our #CellLineOfTheWeek is alpha tubulin! 🧫 Our human iPS cell lines & plasmids – fluorescently-tagged to illuminate cellular structures – are openly available to accelerate discovery: bit.ly/AccessAllenCel… 📦 Distributed by @Coriell_science and Addgene. #OpenScience

‘la médecine actuelle est "une sorte de médecine de la réparation des méfaits de notre société", mais qui ne se soucie pas réellement du bien-être des patients et ne contribue pas réellement à la santé de la population’ interview d’Éric Bonvin rts.ch/info/sciences-…

#WeeklyWebinars are back this week with updates from the HEALEY ALS Platform Trial. Register here: partners.zoom.us/webinar/regist… The ALS Association ALS TDI Muscular Dystrophy Association NEALS Consortium Les Turner ALS Foundation ALS ONE EverythingALS

Lisa Mazzone #merci pour ton #engagement ta #sincerite et ta belle #energie on se rejouit de te voir prendre la tête de nouveaux projets au service des générations futures. rts.ch/info/regions/g…

Scientists at the Crick and @UCL are teaming up to research how DNA damage may contribute to the development of motor neurone disease. Funded by My Name'5 Doddie Foundation and MND Association, the team includes Giulia Tyzack, Nishita Parnandi, The Boulton Lab and Rickie Patani crick.ac.uk/news-and-repor…

early career researcher doing bioinformatics at a london academic institute or university?? join our network for free co-working sessions & more! we have a discord server too more senior people/businesses interested to sponsor/support pls get in touch 😎

Our new napari🔬 annotation tool is out today on Biorxiv. We hope it will help the community. Please spread the word and RT. BIOMAG #deeplearning Réka Hollandi biorxiv.org/content/10.110…

Huge effort, over 5 years now, spearheaded by co-team captains Kelly O'Toole and Ludovica Guetta, featuring the amazing work from our team The Serio Lab and from the teams of Sarah Marzi, Raphaëlle Luisier and Shane Liddelow 🍊. Shout out to our homes at Institute of Psychiatry, Psychology & Neuroscience, The Francis Crick Institute and UK Dementia Research Institute