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I am thrilled to share that our work was published today in Nature Communications. 🔹C3 complement inhibition prevents AMR in sensitized nonhuman primates. Thank you to the Knechtle lab and all collaborators for their hard work. Duke Surgery Duke General Surgery Residency nature.com/articles/s4146…

Pre-existing donor-specific antibody to major histocompatibility complex antigens reduces graft survival. This study shows a belatacept-based maintenance immunosuppression, in combination with desensitization, enables long-term graft survival bit.ly/KID0001732022