Improving diagnostic pathways in patients with podocytopathies is possible. Find out all the latest discoveries in our new review in CKJ Luigi Cirillo Samuela Landini Valentina Raglianti bit.ly/3MG2BuO

Altough with less morbidity, younger KTRs are equally worth to be monitored in their response to SARS-Cov-2 vaccine; total anti-S may be misleading.@FrancescaBeche2 Paola Romagnani American Society of Pediatric Nephrology ESOTtransplant Transplantation IPNA Ped Nephrology ESPN #nephjc journals.lww.com/transplantjour…

Just back from an inspiring #ERA22 in Paris and proud to share our last paper on a genetic-first approach to improve diagnosis and inform prognosis in Bartter and Gitelman syndrome! Viviana Palazzo Valentina Raglianti Samuela Landini Luigi Cirillo Paola Romagnani mdpi.com/1422-0067/23/1…

Proud and humbled to share our recent paper on Nature Communications!It's such a thrill to see the paper finally out! Huge thanks to my PI Paola Romagnani and to Elena Lazzeri How does the kidney adapt to AKI? #polyploidy #AKI #CKD 👇 nature.com/articles/s4146…

A fascinating journey toward #KidneyGenetics thanks to Francesca Becherucci here in Rimini #NephTwitter #SIN2022 SinReni

Congrats to Luigi Cirillo Francesca Becherucci Gianmarco Lugli Samuela Landini and to Elisa Buti and Fiammetta Ravaglia for their review on diagnostic traiectories of podocytopathies and the scheme of Valentina Raglianti on the cover of CKJ

Our new study in JASN describes a diagnostic workflow for genetic kidney diseases using whole-exome sequencing that reaches a diagnostic rate of 67% (with similar rates in pediatric and adult patients), is cost-effective & feasible in a real-world setting bit.ly/JASN076

Excited to share our last work on JASN_News. Genetic diagnosis of kidney diseases is feasible, cost-saving and extremely important for our patients. Thanks to Paola Romagnani Luigi Cirillo Valentina Raglianti Gianmarco Lugli Viviana Palazzo Samuela Landini LetiziaDeChiara

Genetic first”approach can potentially lead to save money up to 40% when applied with the right workflow ensuring high diagnostic rate!Happy to share our work JASN_News: journals.lww.com/jasn/Abstract/… Paola Romagnani Francesca Becherucci Samuela Landini Valentina Raglianti Gianmarco Lugli Viviana Palazzo

Un algoritmo per la diagnosi delle malattie renali genetiche: per i pazienti, per il sistema sanitario, per tutti. ansa.it/canale_salutee… #sanità #difendiamoilsistemasanitario #Genetics JASN_News Regione Toscana Fondazione Meyer Università di Firenze

Happy to see this finally out. The first study able to define the sensitivity and specificity of commercial anti-nephrin Ab by using kidney biopsies as gold standard. Standard Elisas do the job well. kidney-international.org/article/S0085-…

Our new study is out! By STED microscopy on kidney biopsy and ELISA assays we show 1/3 of pediatric and half of adult patients (more in primary FSGS) have autoantibodies against slit antigens different from nephrin. i.e. anti-slit Abs kidney-international.org/action/showPdf…

Anti-slit antibodies define response to therapy and prognosis much better than histopathological lesion patterns even among patients with steroid-resistant nephrotic syndrome kidney-international.org/action/showPdf…

Look how much more important is to know if a patient is genetic or has anti-slit antibodies than if has MCD or FSGS at kidney biopsy. We have finally come to the era of autoimmune, genetic and adaptive podocytopathies. No more MCD or FSGS used as diagnosis!

Thrilled to share our latest in Kidney International Identifying anti-slit diaphragm antibodies is a game changer for patients with steroid-resistant nephrotic syndrome. Together with genetics, we can finally tailor treatments and improve outcomes. kidney-international.org/article/S0085-…

Proud to share our paper in Kidney International! Excited to see our research on anti-slit antibodies in steroid-resistant nephrotic syndrome published—a significant step toward targeted treatments. Huge thanks to my mentor Paola Romagnani and Maria Lucia Angelotti. kidney-international.org/article/S0085-…

Our new study reporting anti-slit autoantibodies against podocin and Kirrel1 in a subset of patients with nephrotic syndrome is out in JASN journals.lww.com/jasn/citation/…

Anti-slit diaphragm antibodies in autoimmune podocytopathy: •Anti-nephrin → frequent in kids •Anti-podocin → in kids & adults •Anti-Kirrel1 → more rare •Some patients have multiple autoantibodies. journals.lww.com/jasn/citation/…

This study was a collaboration with Università di Firenze Universität München Hospital Universitari Bellvitge | HUB Fondazione Meyer Azienda Ospedaliero-Universitaria Careggi. Special thanks to Valentina Raglianti, Maria Lucia Angelotti, Letizia De Chiara, Marco Allinovi, Benedetta Mazzinghi for their key contributions! journals.lww.com/jasn/citation/…