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It will cost Ontario taxpayers $225 million to meet the Ford government's accelerated timeline of getting beer, wine & ready made cocktails to all corner stores and gas stations this fall. This was originally slated to happen in 2026.

Writing the discussion section of your paper

Diphosphorus tetraiodide in action 🎬

My lab has multiple openings for those interested in doing some very cool science in beautiful Colorado! Research assistants (tech/lab manager level): cu.taleo.net/careersection/… Postdoctoral fellows: cu.taleo.net/careersection/… DM or email me if interested and 🙏 share broadly 🪃

How to prepare for your thesis defence (get the course on my profile)

Check out an exciting review by Philip Johnson's lab on cutting-edge biophysical tools for assessing aptamer conformational changes, which are key to advancing biosensors & diagnostics: tinyurl.com/49cy639k #Aptamers #Biophysics #Biosensors #MolecularBiology Cambridge University Press

#AcademicChatter #AcademicX

We always wondered about the possibility of obtaining buffer binding aptamers for failed SELEX. Now we know it is unlikely, especially when Good's buffers are used. A nice collaboration with Philip Johnson pubs.rsc.org/en/content/art…

Great to have played a role in this work with Juewen Liu. Congrats to all involved including Rahith from my lab. #aptamers

Happy to have our latest paper published. Congratulations to all involved! Thanks to our collaborating labs Cameron Mackereth E-Biosensors Lab #ChemBioChem #aptamers Rahith …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/cb…

we isolated a 10 nM Kd aptamer for quinine, with no binding to cocaine. Now, finally, both quinine and cocaine have their own aptamers. Another good collaboration with Philip Johnson, an expert on this topic. Open access, free to read💥 …mistry-europe.onlinelibrary.wiley.com/doi/10.1002/ch…

Correlation Between NMR Coupling Constants and σ-Donating Properties of N-Heterocyclic Carbenes and Their Derivatives (Radhika Gupta and Gilles Frison) #NMRChat #openaccess 🔓 onlinelibrary.wiley.com/doi/10.1002/ch…

Glad to see our new J. Am. Chem. Soc. paper online on New Year Day! Using Sc3+, a visiting PhD student Jin Wang obtained an aptamer with different affinities and binding and dissociation kinetics to rare earth metals. Thanks Philip Johnson and Rahith for NMR! doi.org/10.1021/jacs.4…

Our aptamer for acrylamide has only mM affinity. After reacting acrylamide with xanthydrol to form a covalent adduct, a new aptamer with nM affinity for the adduct was obtained. Published ACS Analytical Chemistry Journals pubs.acs.org/doi/full/10.10…

I think this is the first time that Irving-Williams series is seen in a nucleic acid. Should be an interesting metal binding site. Check out our new paper Chemical Science, another good collaboration with Philip Johnson and Rahith pubs.rsc.org/en/content/art…

Led by PhD student Yachen Xie, we obtained aptamers for bilirubin and biliverdin. Took us two years, a lot of details, check it out! Nice NMR from Philip Johnson and Rahith pubs.acs.org/doi/10.1021/ac…

New paper out as part of our ongoing collaboration with Juewen Liu at Waterloo. Interesting to see aptamers for ligand targets with such subtle structural differences. Great work by everyone involved Juewen Liu #aptamer