What if we could map every cell in the body, revealing its location and molecular identity? In this @NatureMethods perspective, we discuss the new era of 3D-omics by tissue clearing and AI, called Deep 3D Histology: rdcu.be/dNBe8 PDF: bit.ly/3WaD0QU 🧵👇🏼

🩸Blood vessels! Happy to present two of our vessel papers recently accepted at MICCAI24 - 🤖💡"Simulation-Based Segmentation of Blood Vessels in Cerebral 3D OCTA Images" arxiv.org/abs/2403.07116 - 🌊🛟"3D Vessel Graph Generation Using Denoising Diffusion" arxiv.org/abs/2407.05842

I'm excited to introduce MouseMapper, an AI tool I've been working on in the past months, that enables us to study whole body changes in mice! Check out Ali Max Erturk's tweetorial about what we did, and why it matters!

Excited to be a part of the team behind MouseMapper! 😎 Our new AI tool uncovers how diseases like obesity impact the body at a cellular level, from facial nerves to widespread inflammation 🧫🔬 Check our preprint 👇🏻

Super excited to share our latest preprint with you 🤩 We've tackled the challenge of visualizing obesity-induced changes in peripheral nerves and immune cells on the whole-body scale and developed an AI-powered pipeline to precisely quantify these changes.

Very excited to share our newes preprint! A holistic view of the impact of a disease on the whole body on the cellular level!

Very excited to share our newest preprint! Our new AI tool MouseMapper provides a pipeline to quantify the changes in peripheral nerves and immune cells in HFD mice.

Every cell matters! Check out our new study on obesity where we used deep learning-based quantitative analysis on whole bodies of obese mice as well as we applied spatial proteomics to extract underlying molecular mechanisms of structurally perturbed nerves!

Our new study shows that SARS-CoV-2 spike protein accumulates & persists in the body for years after infection, especially in the skull-meninges-brain axis, potentially driving long COVID. mRNA vaccines help but cannot stop it🔬🧠🦠🧵👇Cell Host & Microbe cell.com/cell-host-micr…

SCP-Nano: Advancing Precision Medicine with Nanocarrier Visualization How can life-saving therapies reach their target cells without harmful side effects? 👉t1p.de/muluc 💡Researchers at #HelmholtzMunich, Universität München, and TU München have developed SCP-Nano

LNP/mRNA therapeutics and AAV-based approaches require cell-level precision to achieve success without significant toxicity to other cells. To enable this, we now introduce SCP-Nano🤗 in Nature Biotechnology: an AI-based technology for precision nanotechnology. nature.com/articles/s4158…

Nanocarrier imaging at single-cell resolution across entire mouse bodies with deep learning go.nature.com/4gNLjeC

The validation phase of this year’s BraTS Inpainting Challenge is on! #BraTS2025 #Lighthouse #MICCAI Looking forward to seeing your creative and innovative ideas! synapse.org/Synapse:syn641…

Interested in generating graphs that preserve the semantic (& structural) constraints for biological graphs? Check out our paper "Semantically Consistent Graph Generation" – accepted in MICCAI 25 !

We have developed DELIVR, a user-friendly deep-learning pipeline for automatically detecting and analyzing cells from whole-brain images to map neuronal activity via cFOS. DELIVR uses virtual reality to substantially accelerate the generation of training data and is accessible to

Have a look at our data and join us at #MICCAI2025!

Amazed to share our new study published in Cell revealing how the liver contributes to weight loss in cancer via disruption of a circadian regulator and secretion of catabolic factors. Big thanks to Søren Fisker Schmidt, S. Herzig, Mauricio Berriel Diaz 🧵👇 cell.com/cell/fulltext/…

Very cool challenge at #MICCAI 2025! Join us and dive deep into some complex structure segmentation! 🧠

We are introducing LipiGo 🤗 A programmable DNA–lipid nanocarrier 🧬 with built-in targeting logic. It de-targets the liver and redirects mRNA delivery into lymphoid organs, enhancing therapies requiring the immune system. by cerenkimna Karoline biorxiv.org/content/10.110… 1/n