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Check out our cool new paper from RaminHerati on how Tfh in the blood can act as "biosensors" of underlying inflammatory status. A new way to use the immune system to tell use about baseline health of the host. #ImmuneHealth. cell.com/cell-reports-m…

Incredibly appreciative of this award. We are starting on these questions right away, and I can’t wait to find out the answers.

Wonderful news for an amazing group of scientists. Congrats Laura Vella and Alex Huang (we have to get him on Twitter!).

New data showing solid durability of cellular immune memory at 6 months after mRNA vaccination. Strong memory CD4 T cells and even better memory B cells. New work from Rishi Goel Mark Painter Sokratis Apostolidis and Divij. UPenn #ImmuneHealth biorxiv.org/content/10.110…

Thanks to all of the members of the NYU Vaccine Center who helped us get this work done! science.org/doi/10.1126/sc…

Woaw finally it is out! Such a great immune profiling paper with deep insight of human T cell differentiation! Big congrats to Dr. Josephine Giles and E. John Wherry!

Thank you Parker Institute for Cancer Immunotherapy and The V Foundation for Cancer Research for this incredible honor as I transition to my new role as junior faculty at Penn Medicine and CHOP Center for Computational and Genomic Medicine! Thank you also to E. John Wherry and Wherry Lab for your years of incredible mentorship and support! x.com/parkerici/stat…

Congrats to Jose Campos on being one of the 2022 #GilliamFellows! I’m so lucky to mentor Jose on his thesis journey and join this amazing community. Discoveries and insights ahead — all made possible by supporting great trainees like Jose! HHMI Penn IGG CHOP Research

So excited to see our study on the effects of immunotherapy on the flu vaccination out! Thanks to E. John Wherry, DavidKnorrMDPhD, and all of the collaborators in the Wherry and Ravetch labs and at UPenn and MSKCC for helping bring this all together nature.com/articles/s4159…

Another cool example of #ImmuneHealth in action. New studies from RaminHerati about PD-1 in controlling vaccine responsive Tfh. These Tfh can also predict autoimmunity when patients are treated with aPD-1. Great collab w DavidKnorrMDPhD & J.Ravetch nature.com/articles/s4159…

Lymphocytes have been genetically sequenced in higher resolution than ever before, uncovering more information about how mutations in these cells may influence the #ageing process and the development of certain #cancers 🔎🧬 bit.ly/3PgBdV3

Beautiful work from Dr. Josephine Giles and Wherry Lab! The clear resolution of memory branches in scATAC-seq (and relative lack thereof in scRNA-seq) is very striking. Congrats to everyone who contributed 🎉🎉🎉

👏 Way to go E. John Wherry, center co-director of PICI Penn Medicine. A well-deserved honor for your impact on cancer immunology! #PICINetwork #AACR23 #MedTwitter #MedEd #MedNews

Why do some people have strong immunity after vaccination and others don't? Join our team as a post-doc to study this! tinyurl.com/nyuPostdoc and teamtfh.org for more. Please RT! #immunology #postdoc

In vitro models of CD8 T cell exhaustion make high-throughput interrogation easy, but can they be used to discover real Tex biology with therapeutic relevance? Read to find out! In our new work from the E. John Wherry lab, out now at Science Immunology, we... bit.ly/45yOFMB

A new tutorial on how to reorder rows & columns of a heatmap has been added to my "Friends don't let friends make bad graphs" repository. Link to tutorial: github.com/cxli233/Friend… Link to "Friends don't let friends make bad graphs": github.com/cxli233/Friend…

In our NEW NEJM publication we found that 1) #Mpox antibody responses after #JYNNEOS vaccination are similar in people with & without #HIV. 2) Antibody #halflife after vaccination was 107 days. 3) No differences in route of 💉 administration! nejm.org/doi/full/10.10…

extremely excited to share our new story on the impact of JAK inhibition on responses to immune checkpoint blockade in lung cancer patients! 🧬🧑‍🔬 thread on our main findings 🧵 1/n science.org/doi/10.1126/sc…

Exciting new paper from Divij highlighting the ability to drug the "immunopharmacology" of checkpoint blockade to improve responses in NSCLC. aPD1+transient JAK inhibition. A great collaboration with Andy Minn. Similar work from J.Teijaro scripps …w-science-org.proxy.library.upenn.edu/doi/pdf/10.112…

🚀Very excited to announce that the Apostolidis Lab will open up its doors on July 1st Penn Medicine! We will be focusing our efforts on understanding fundamental drivers of autoimmunity using unique human cohorts and mechanistic mouse models. #Autoimmunity #Rheumatology