Janani Rangaswami (@rangaswj) 's Twitter Profile
Janani Rangaswami

@rangaswj

Nephrologist, Professor of Medicine, GWU, Chief of Nephrology, DC VA Medical Center, Immediate Past Chair@kidneyinCVD @AHA, #CKMH@AHA, Views =My own

ID: 1009197513860100097

calendar_today19-06-2018 22:13:32

1,1K Tweet

1,1K Followers

682 Following

Muthu Vaduganathan (@mvaduganathan) 's Twitter Profile Photo

🔥 #CONFIDENCE in NEJM Simultaneous initiation of #SGLT2i + #nsMRA safely and rapidly delivers in patients with CKD & T2D A new age of combination therapies has arrived in #CKM care #ERA25 nejm.org/doi/full/10.10…

🔥 #CONFIDENCE in <a href="/NEJM/">NEJM</a>

Simultaneous initiation of #SGLT2i + #nsMRA safely and rapidly delivers in patients with CKD &amp; T2D

A new age of combination therapies has arrived in #CKM care #ERA25

nejm.org/doi/full/10.10…
Rajiv Agarwal MD, MS (@agarwalrajivmd) 's Twitter Profile Photo

More than 50% reduction in uacr with combo and about 30% with each component that is empagliflozin and finerenone. Time to consider simultaneous initiation of combination therapy in ckd and t2d as in hfref and stage 2 hypertension.

Muthu Vaduganathan (@mvaduganathan) 's Twitter Profile Photo

#NUDGECKD in Circulation #ERA25 by Kristoffer Grundtvig Skaarup & Tor Biering-Sørensen, MD, MSc, MPH, PhD Nationwide 2x2 Pragmatic Implementation Mega-Trial 👥 n=22,617 🇩🇰 adults w #CKD 🥼n=1540 General practitioners Electronic nudges did not improve uptake of #RASi or #SGLT2i versus usual care ahajournals.org/doi/10.1161/CI…

#NUDGECKD in <a href="/CircAHA/">Circulation</a> #ERA25 by <a href="/KristofferSkaar/">Kristoffer Grundtvig Skaarup</a> &amp; <a href="/TorBiering/">Tor Biering-Sørensen, MD, MSc, MPH, PhD</a>

Nationwide 2x2 Pragmatic Implementation Mega-Trial
👥 n=22,617 🇩🇰 adults w #CKD
🥼n=1540 General practitioners

Electronic nudges did not improve uptake of #RASi or #SGLT2i versus  usual care

ahajournals.org/doi/10.1161/CI…
Brendon Neuen (@brendonneuen) 's Twitter Profile Photo

Combination therapy as a new standard of care in CKD - multiple trials testing new therapies in combo with SGLT2i - ARCTIC/PACIFIC trials: Baxdrostat/dapa vs. dapa - EASi-KIDNEY: Vicadrostat/empa vs. empa - ZENITH-HP: Zibotentan/dapa vs. dapa doi.org/10.1093/ndt/gf… #ERA25

Combination therapy as a new standard of care in CKD - multiple trials testing new therapies in combo with SGLT2i

- ARCTIC/PACIFIC trials: Baxdrostat/dapa vs. dapa
- EASi-KIDNEY: Vicadrostat/empa vs. empa
- ZENITH-HP: Zibotentan/dapa vs. dapa

doi.org/10.1093/ndt/gf…

#ERA25
NYACP (@newyorkacp) 's Twitter Profile Photo

📣 Medical students and residents are the future of medicine. Your voice matters. NYACP and @acpimphysicians can help you speak up and lead. #MedTwitter #ACPAdvocacy #FutureOfMedicine Tamara Goldberg

Janani Rangaswami (@rangaswj) 's Twitter Profile Photo

It was wonderful to visit The George Institute for Global Health and Royal North Shore hospital and meet with Brendon Neuen and colleagues ! Enjoyed our discussions on #Cardiorenal Syndrome, decongestion and #GDMT, and beyond !

It was wonderful to visit <a href="/georgeinstitute/">The George Institute for Global Health</a> and Royal North Shore hospital and meet with <a href="/brendonneuen/">Brendon Neuen</a> and colleagues ! Enjoyed our discussions on #Cardiorenal Syndrome, decongestion and #GDMT, and beyond !
Brendon Neuen (@brendonneuen) 's Twitter Profile Photo

Absolutely delighted to host Prof Janani Rangaswami in Sydney this week - great talks and discussions with our faculty, nephrology trainees, and overseas visiting fellows from across the region - a few more pics from me! The George Institute for Global Health Northern Sydney Local Health District NORTH Foundation

Absolutely delighted to host Prof <a href="/RangaswJ/">Janani Rangaswami</a> in Sydney this week - great talks and discussions with our faculty, nephrology trainees, and overseas visiting fellows from across the region - a few more pics from me! <a href="/georgeinstitute/">The George Institute for Global Health</a> <a href="/NthSydHealth/">Northern Sydney Local Health District</a> <a href="/north_fndn/">NORTH Foundation</a>
AJKD (@ajkdonline) 's Twitter Profile Photo

This Core Curriculum explores commonly implicated pathophysiological mechanisms in kidney dysfunction in heart failure and discuss principles behind effective decongestion and assessment of adequacy of natriuresis: bit.ly/434spfa (FREE) Kevin Bryan Lo A. Janakiraman Janani Rangaswami

This Core Curriculum explores commonly implicated pathophysiological mechanisms in kidney dysfunction in heart failure and discuss principles behind effective decongestion and assessment of adequacy of natriuresis:

bit.ly/434spfa (FREE)

<a href="/KevinBryanLo/">Kevin Bryan Lo</a> <a href="/UVoverP/">A. Janakiraman</a> <a href="/RangaswJ/">Janani Rangaswami</a>
Kidney in Cardiovascular Disease (@kidneyincvd) 's Twitter Profile Photo

.Kidney in Cardiovascular Disease friends! Come gather in Baltimore for #Hypertension25! Don't miss out on the opportunity to gain cross-disciplinary connections and learn more about empowering hearts and uniting against #Hypertension this September Register: bit.ly/Hypertension25 #AHAScience

.<a href="/KidneyInCVD/">Kidney in Cardiovascular Disease</a> friends! Come gather in Baltimore for #Hypertension25! 
Don't miss out on the opportunity to gain cross-disciplinary connections and learn more about empowering hearts and uniting against #Hypertension this September
Register: bit.ly/Hypertension25
#AHAScience
Ahmed Bennis (@drbennisahmed) 's Twitter Profile Photo

Interconnected pathways and emerging therapies in chronic kidney disease and heart failure: A comprehensive review Early diagnosis and intervention are important to slow CKD progression and reduce HF events. Shared therapeutic targets for CKD and HF include the renin–angiotensin

Interconnected pathways and emerging therapies in chronic kidney disease and heart failure: A comprehensive review

Early diagnosis and intervention are important to slow CKD progression and reduce HF events. Shared therapeutic targets for CKD and HF include the renin–angiotensin
Brendon Neuen (@brendonneuen) 's Twitter Profile Photo

SGLT2i in CKD: impact beyond kidneys 🔻 15% all-cause hospitalizations ✅ Consistent across eGFR, UACR & diabetes 🏥 ~36 fewer hospitalizations per 1000 pt-years Large absolute gains for patients & health systems. Meta-analysis in ASN Publications: 🔗 journals.lww.com/cjasn/abstract…

SGLT2i in CKD: impact beyond kidneys

🔻 15% all-cause hospitalizations
✅ Consistent across eGFR, UACR &amp; diabetes
🏥 ~36 fewer hospitalizations per 1000 pt-years

Large absolute gains for patients &amp; health systems.

Meta-analysis in <a href="/asnpublications/">ASN Publications</a>:

🔗 journals.lww.com/cjasn/abstract…
Brendon Neuen (@brendonneuen) 's Twitter Profile Photo

New episode this week! We discuss pragmatic trial infrastructure in Denmark, implementation science in nephrology and how new approaches to recruitment can improve access, equity and representation in trials #kidneycompass