Very interesting paper to use human neuron xenografts (human-mouse chimeric brain) to gain new insights on human neuronal cell loss in Alzheimer's disease, which is difficult to model in animals. science.org/doi/10.1126/sc…

Excited to be DataBlitzing together with L Peruzzotti-Jametti some of our most recent human work with #neuralstemcell #transplants in people with #progressiveMS at Society for Neuroscience (SfN) congress | Zoom link to the 'HOT TOPICS' IN STEM CELL BIOLOGY Symposium on the flyer

Our lab is recruiting graduate students to start in the Summer or Fall of 2024. If you are interested in preclinical research related to substance use disorders and looking for a lab for graduate school please reach out.

LRRC37B receptor, a human-specific modifier of cortical neuron excitability

Microglia enhance post-anesthesia neuronal activity by shielding inhibitory synapses

I am excited that our first review paper is online in the Neuroscience Bulletin. rdcu.be/dAUNO In it, we discussed recent advances in using human iPSC-based human–animal chimeras to model neurological disease and test cell therapy. Congratulations to Yanru and Jenna!

It’s a great honor to be with Dr Mattson The National Institute on Aging (NIA) Johns Hopkins University at his Brain Ponderings podcast for general audience interested in neuroscience. Our conversation on microglia goes quite deep. Thanks Dr Mattson’s insight questions and tremendous efforts! youtu.be/oL0Hj8ddMEg?si…

Human iPSC 4R tauopathy model uncovers modifiers of tau propagation

Microglia pack a toolbox for life 🧰🛠️ Trends in Immunology Kristine Zengeler sciencedirect.com/science/articl…

We're excited to receive our first NIH U01 grant as MPI with Dr. Chongli Yuan (PI) at Purdue to study environmental and genetic interactions in Alzheimer's disease using iPSC 2D and chimeric brain models. Thank you to my lab for their hard work and to everyone for your support!

The second session of the NIH Alzheimer’s Research Summit, Enabling a Precision Environmental Health Approach to Risk Reduction and Disease Prevention, is starting now. Watch the event: go.nia.nih.gov/3XGC6O1 #ADSummit24 UW–Madison Columbia University

Can we use CRISPR screens to identify genes that drive neural stem cell aging? Super excited to see this work published nature! Huge congrats to Tyson @ruetz_tyson, Angie Pogson, Chloe Kashiwagi, and all authors! Great collaboration with Michael C Bassik! nature.com/articles/s4158…

The Center for Neuroimmunology and Glial Biology CNG at UTHealth Houston McGovern Med School has multiple open-rank faculty openings! Come to join us to explore the non-neuronal cells and harness the power of brain immunity. DM or email me if you are interested. nature.com/naturecareers/…