Rasmus Krogh Norrild
@rasmusnorrild
Postdoc with @alexander_dtu at @DTUbioengineer and former student at #LinderstrømLang Center for Protein Science, UCPH @uni_copenhagen
ID: 2190251411
21-11-2013 18:31:00
111 Tweet
185 Followers
267 Following
How do you stabilize a stable protein (ΔG=48 kJ/mol), when your assay is already maxed out? Read how Rasmus Krogh Norrild & Kristoffer Johansson combined a folding sensor, mutational scanning and our GMMA algorithm to improve stability (ΔG=69 kJ/mol; Tm~150°C) biorxiv.org/content/10.110…
Now it is possible to read the final version in Cell Reports Methods! cell.com/cell-reports-m…
Great collaboration between the Copenhagen University friends Jakob Winter Larsen , Kresten Lindorff-Larsen Kristoffer Enøe Johansson and Charlotte O'Shea. With a cool methodological approach to stabilize proteins. Supported by structural work performed at DTU Bioengineering, #research.
Alpha-helical peptides captured by designed proteins. Biomedical applications abound. Special thanks from us to Joseph Watson --- new binders from peptide sequence alone. Congrats to the big team Susana Vazquez Torres Phil Leung @fabian_hink David Juergens biorxiv.org/content/10.110…
Join us! PhD position open! Henriette E Autzen and I are offering one-hell-of-a- project: using high-end membrane protein science to enable the screening of ultra-large libraries of cyclic peptides. Funded by DK Frie Forsk.fond, in collaboration with @LabPless. employment.ku.dk/phd/?show=1594…
If you are working or planning to work on alpha synuclein phase separation, then you will find my new article insightful. @alpha_synuclein Nature Chemistry DTU Bioengineering Also go through our research journey here: protocolsmethods.springernature.com/posts/mass-pho…
It's finally out ;) I'm happy to share the results of our work on comparing different protein stabilization strategies which resulted in three highly thermostable haloalkane dehalogenases with improved catalytic efficiencies. Loschmidt Laboratories, Masaryk University pubs.acs.org/doi/full/10.10…
Finishing a PhD is a tough job, but also an amazing journey of growth and learning. It was therefore amazing to conclude the thesis by being able to discuss my work with KnowlesLab Cambridge, Ben Lehner, and Rune Busk Damgaard! Thanks to all involved - especially my supervisors!!
Was a delight to witness the development of these amazing helix-binding proteins. Congratulations to Susana Vazquez Torres Preetham Venkatesh Phil Leung Joseph Watson and all on the team from the David Baker lab. nature.com/articles/s4158…
Publication 🧵: Excited and proud to share that our work using deep network hallucination to scaffold an enzyme active site has been published (ACS Synthetic Bio #EditorsChoice)! Dive in with us! 👇doi.org/10.1021/acssyn…
In this comprehensive review now published in The Journal of Chemical Physics , Alex (@biophysics_dtu) and I highlight the recent advances in the experimental methods to quantitatively study biomolecular phase separation. Really happy to finally see it online! doi.org/10.1063/5.0190…
Great timing! Our TDIPS method to study biomolecular condensates highly efficiently is now published in Angewandte Chemie, while I am attending an amazing conference EMBL Events #EESPhaseSeparation. Check out the paper here: onlinelibrary.wiley.com/doi/10.1002/an…
Check out Rasmus Krogh Norrild's work with Alex Buell @biophysics_dtu and Joseph Rogers developing and using Condensate Partitioning by mRNA-Display to probe phase separation of ~100.000 sequences, and @SoBuelow simulations to support and analyse the experiments
mRNA display continues to astound. Fantastic collaboration with Alexander Buell, led by the peerless Rasmus Krogh Norrild. ~100,000 peptides and their propensity to join the phase separation of a model disordered protein. doi.org/10.1101/2024.1…