We are excited to welcome at UConn Health Dr Pluchino lab - Regenerative Neuroimmunology to be our Inaugural Petit Family Visiting professor and Distinguished lecturer in #MS and #Neuroimmunology in #Farmington , #MS #progression #stem #cells ISNI-The International Society of Neuroimmunology National MS Society

Honored to be the 2025 Petit Family Visiting Professor in #MS at UConn Health! Looking forward to connecting with colleagues Jaime Imitola MD., FAAN ISNI-The International Society of Neuroimmunology, National MS Society, RESTORE & Cam Neuroscience. Excited to share & learn! #MultipleSclerosis #Research #UConnHealth | we lost a cell again ;)

We are recruiting at all levels. If you are interested in using cool technologies to study immune recognition in the context of host microbe interactions, autoimmune diseases and cancer, welcome to reach out!

📢 paper - a new class of RIPK1 inhibitors. Lots of with here, with structure of it bound to RIPK1, biochemistry and more! Was fun being part of this with Tate group and many others. pubs.acs.org/doi/10.1021/ac…

Hi everybody! I am super excited to share the work done during my PhD published in @nature today! We describe a new mechanism of self- vs. non-self RNA discrimination by showing how N-glycans shield glycoRNAs from stimulating endosomal RNA sensors nature.com/articles/s4158…

Sweet Disguise: Body Hides RNA With Sugar today.uconn.edu/2025/08/sweet-… Thanks to UConn Research and Kim Krieger for covering our glycoRNA paper! Vincent Graziano

Beautiful work to show surface RNA glycosylation (glycoRNA) as an important mechanism for the innate immune system to discriminate self and non-self. Congrats to Vijay and the team!

Vijay Rathinam Vincent Graziano discovers why RNA undergoes glycosylation: N-glycans on glycoRNAs hide self-RNA from endosomal TLRs promoting ‘silent’ clearance of dead cells nature nature.com/articles/s4158…

#GlycoPower! Vijay Rathinam @raflynn5 Vincent Graziano show nature that N-glycosylation of host small-RNA at the cell surface prevents immune recognition by TLR3 and TLR7 upon apoptotic cells uptake, preventing autoinflammation! nature.com/articles/s4158…

Congrats Vijay and team! Fantastic work!

N-glycans in a new role and, perhaps, another glyco-checkpoint !N-glycans on glycosylated RNAs hide self-RNA from endosomal Toll like receptors promoting silent clearance of dead cells | Nature

📰IN THE NEWS | "Certain RNA modifications could contribute to the development of autoimmune disorders" ft. UConn Health's Vijay Rathinam, DVM, PhD, and graduate student Vincent Graziano (via EurekAlert!) eurekalert.org/news-releases/…

Very interesting AND with a lot of potential applications!

How does our immune system distinguish our own RNA from that of dangerous invaders? As UConn School of Medicine researchers and colleagues report, the answer is short and sweet: sugar. today.uconn.edu/2025/08/sweet-…

Nature research paper: RNA N-glycosylation enables immune evasion and homeostatic efferocytosis go.nature.com/4m6slCP

Thrilled that our paper is finally in press Science Magazine!! *Platelets sequester cell free DNA, including free fetal and tumour-derived DNA* Tweetorial from Lauren Murphy below. Check out the news feature science.org/content/articl… and terrific editorial from Dennis Lo