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FDA identified only 4 out of 17 commercial pediatric oncology trials (1997-2020) included PROs (in single arm trials, with PRO as exploratory endpoint). FDA makes a strong recommendation for inclusion of PROs to capture the child's voice. academic.oup.com/jnci/advance-a…

Looking forward to our chat with the FDA tomorrow about the Pediatric PRO-CTCAE system to capture the child's voice in self-reporting symptomatic AEs while undergoing cancer treatment. #PRO fda.gov/advisory-commi…

We need to listen to parental and child voices when we determine what it means to be eligible for a clinical trial. Proud to work w Duke Department of Population Health Sciences Sharon M. Castellino Justin Baker et al. UPMC Children's Hospital of Pittsburgh Pitt Department of Pediatrics Peds Heme/Onc at UPMC Children's Hosp Pittsburgh #pedpc acsjournals.onlinelibrary.wiley.com/doi/abs/10.100…

Clinicians & children with #cancer report symptom burden differently: clinicians consistently downgrade symptoms. Dr. Bryce Reeve & team find enhancing the child’s voice through surveys can improve cancer care and identify effective treatments. bit.ly/3Lz7fKx

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