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Check out this hand-drawing mini-ToC-style of #CRBNmidi created by the incredible Alena Kroupová, it's so cool! Centre for Targeted Protein Degradation

"In 2023, Tuberculosis (TB) probably returned to being the world’s leading cause of death from a single infectious agent, following 3 years in which it was replaced by coronavirus disease (COVID-19), and caused almost twice as many deaths as HIV/AIDS." buff.ly/3C3Hsuw

Taosheng Chen's lab developed a versatile fluorescent probe for nuclear receptor CAR and multiple kinases. #ACSMedChemLett go.acs.org/bvm

Induced Proximity, in the Lab and in the Clinic | Science | AAAS science.org/content/blog-p…

Structural basis for C-degron selectivity across KLHDCX family E3 ubiquitin ligases, now out Springer Nature Nature Communications Awesome collaboration with @sagarchittori . Structural Biology at St. Jude Children's Hospital Max Planck Institute of Biochemistry (MPIB) St. Jude Research #TPD #PROTAC #SchulmanLab rdcu.be/d0h2G

If you have a spare 15 min, in honour of World AMR Awareness Week (#WAAW) here's a great documentary on how antibiotic misuse in food production is helping to drive antimicrobial resistance (with a few quotes in my messy office). Institute for Molecular Bioscience CO-ADD Antibiotics UQ News AAMRNet

STAT's Helen Branswell 🇨🇦 sets the table for where we stand with #H5N1 #birdflu in North America.

🆕️⚡️⚡️Hello Sader et Al Antimicrobial susceptibility of enterobacterales causing bloodstream infection in US medical centres: comparison of aztreonam avibactam with beta-lactams active against carbapenem resistant enterobacterales CRE #idxposts bmcinfectdis.biomedcentral.com/articles/10.11…

Outstanding work!

There is a recall process in the charter that, while narrow and difficult, covers any and every elected person in Shelby County with the apparent exception of school board members. The barriers to holding elected officials accountable are ridiculous and must change.

The final paper of the year, our study of tetracycline analogs for mycobacteria infections doi.org/10.1016/j.tube…

Many people talk about the 'Golden Age of Antibiotics' but I hadn't seen it visualized properly. How abundant was antibiotic development during that time period? How many types of antibiotics were developed? So I visualized it myself!

Advancing global antibiotic research, development and access | Nature Medicine nature.com/articles/s4159…

The Roberts Lab is looking for highly motivated, intellectually engaged candidates with an interest in #ChromatinBiology to fill a Researcher position. Check out the link below and feel free to reach out with any inquiries! talent.stjude.org/careers/jobs/J…

This will probably be a 🧵 Going through financials for Whole Child strategies, the 501c3 run by Memphis Shelby County Schools Board Member McKinney.

Disappointing results - an example of the challenge in developing good antibacterial vaccines.... Sanofi takes $250M hit after gamble on J&J E. coli vaccine ends in phase 3 failure fiercebiotech.com/biotech/sanofi…

Building your mentor network is less like a graduation and more like an amusement park. For more career advice, check out the link in my bio.

Charles Mullighan, MBBS, MSc, MD, senior deputy director of the St. Jude Comprehensive Cancer Center, has been elected as a Fellow of the Royal Society of London, the world’s oldest scientific society, for his contributions to leukemia research.