Rick Bright (@rickabright) 's Twitter Profile
Rick Bright

@rickabright

Practical, Innovative, Hyper-focused on saving lives. Immunologist, Virologist, Pandemic Nemesis. Posts are mine.

ID: 822496079274975232

calendar_today20-01-2017 17:28:41

10,10K Tweet

49,49K Followers

2,2K Following

Sayed Abdel-whab (ORCID: 0000-0003-2103-0922) (@sayedabdelwhab) 's Twitter Profile Photo

🚨 New HPAI H5N9 outbreak in the Philippines 🇵🇭 🦆 Domestic ducks in rice fields likely exposed to wild birds 🦠 First detection of H5N9 in the country 📆 Start: 15 Apr 2025 | Confirmed: 30 Apr 📊 110 susceptible | 84 dead | 26 culled 📌 Event ongoing wahis.woah.org/#/in-review/64…

Dr Richard Hirschson (@richardhirschs1) 's Twitter Profile Photo

China reports more H9N2 and H10N3 avian flu cases. Old clades of #H5N1 continue to mutate/evolve. Bovine B3.13 and D1.1 clades of H5N1 continue to spread in the US. There has never been a higher global burden of #BirdFlu.

China reports more H9N2 and H10N3 avian flu cases.
Old clades of #H5N1 continue to mutate/evolve.
Bovine B3.13 and D1.1 clades of H5N1 continue to spread in the US.
There has never been a higher global burden of #BirdFlu.
Dr Richard Hirschson (@richardhirschs1) 's Twitter Profile Photo

#H5N1 #BirdFlu is adapting to become a SwineFlu virus. Trial confirms limited spread of bovine H5N1 clade 2.3.4.4b in pigs.👇👇 Pigs are excellent ‘mixing vessels’ for BirdFlu viruses, promoting transition from being an Avian gut virus to a human lung virus. Rick Bright

#H5N1 #BirdFlu is adapting to become a SwineFlu virus.
Trial confirms limited spread of bovine H5N1 clade 2.3.4.4b in pigs.👇👇
Pigs are excellent ‘mixing vessels’ for BirdFlu viruses, promoting transition from being an Avian gut virus to a human lung virus.
<a href="/RickABright/">Rick Bright</a>
Helen Branswell 🇨🇦 (@helenbranswell) 's Twitter Profile Photo

#USDA reported 2 new #H5N1 #birdflu infected dairy herds in Texas today, the first there since last Dec. Anyone know if these are new spillovers? it isn't easy to get that kind of info from USDA anymore. Cumulative national total: 1065 herds in 17 states.

#USDA reported 2 new #H5N1 #birdflu infected dairy herds in Texas today, the first there since last Dec. Anyone know if these are new spillovers? it isn't easy to get that kind of info from USDA anymore. 
Cumulative national total: 1065 herds in 17 states.
Helen Branswell 🇨🇦 (@helenbranswell) 's Twitter Profile Photo

#CDC has been informed of another child who died from #flu this past winter. This brings the season's death toll in kids so far to 227, a record for a non-pandemic year. The child died in early January. CDC says that 90% of these kids weren't fully vaccinated against flu.

#CDC has been informed of another child who died from #flu this past winter. This brings the season's death toll in kids so far to 227, a record for a non-pandemic year. The child died in early January. CDC says that 90% of these kids weren't fully vaccinated against flu.
Helen Branswell 🇨🇦 (@helenbranswell) 's Twitter Profile Photo

#USDA confirmed 5 more #H5N1 #birdflu infected dairy herds in Idaho. Moving fast there. 70 herds have tested positive since late February. Cumulative national total: 1070 herds in 17 states. aphis.usda.gov/livestock-poul…

#USDA confirmed 5 more #H5N1 #birdflu infected dairy herds in Idaho. Moving fast there. 70 herds have tested positive since late February.
Cumulative national total: 1070 herds in 17 states. aphis.usda.gov/livestock-poul…
JusDayDa (@jusdayda) 's Twitter Profile Photo

Idaho Dairy Herds with Avian Flu (1st infections only) 2024 wave - 203 days - 35 herds 2025 wave - 80 days - 70 herds 2024 was Boisie (orange) 2025 is Twin Falls, South Central (green) Drought + Migration + Flu = Spread Looking forward to typing and comparison to Brazil strain

Idaho Dairy Herds with Avian Flu (1st infections only)
2024 wave - 203 days - 35 herds
2025 wave -    80 days - 70 herds
2024 was Boisie (orange)
2025 is Twin Falls, South Central (green)
Drought + Migration + Flu = Spread
Looking forward to typing and comparison to Brazil strain
JusDayDa (@jusdayda) 's Twitter Profile Photo

Avian Flu in Dairy Cows Shown as a percentage of State Herds over time California has "ended" regular updates CRITICAL UPDATE -Wisconsin will start testing all 5,000+ herds once per month as Drought looks likely this summer -Brazil's bird migration moving through Wisconsin now

Avian Flu in Dairy Cows
Shown as a percentage of State Herds over time
California has "ended" regular updates

CRITICAL UPDATE
-Wisconsin will start testing all 5,000+ herds once per month as Drought looks likely this summer
-Brazil's bird migration moving through Wisconsin now
Dr. Saskia Popescu (@saskiapopescu) 's Twitter Profile Photo

Evolution, spread and impact of highly pathogenic H5 avian influenza A viruses | Nature Reviews Microbiology nature.com/articles/s4157…

Ryan Hisner (@longdeserttrain) 's Twitter Profile Photo

Australia, Taiwan, and Japan seem to be the major molnupiravir users these days. Sometimes it's hard to tell if a new MOV sequence is from recent MOV use or treatment from the past—like this recent FL.20.1 whose closest relatives on the tree were collected ~1 year ago. 1/4

Australia, Taiwan, and Japan seem to be the major molnupiravir users these days. Sometimes it's hard to tell if a new MOV sequence is from recent MOV use or treatment from the past—like this recent FL.20.1 whose closest relatives on the tree were collected ~1 year ago.    1/4
Ryan Hisner (@longdeserttrain) 's Twitter Profile Photo

The molnupiravir-associated nucleotide contexts of the mutations in this one—particularly the G->A contexts—leave little doubt MOV was used here. Figures from Theo Sanderson 's MOV nuc context calculator: movbranchapp.streamlit.app 2/4

The molnupiravir-associated nucleotide contexts of the mutations in this one—particularly the G-&gt;A contexts—leave little doubt MOV was used here.  Figures from
<a href="/theosanderson/">Theo Sanderson</a> 's MOV nuc context calculator: movbranchapp.streamlit.app        2/4
Ryan Hisner (@longdeserttrain) 's Twitter Profile Photo

This is very much a trend in recent MOV sequences (first noted by Sakaguchi Hitoshi), and not a happy one. MOV is intended to kill the virus by inducing harmful mutations. If instead MOV mutations are being positively selected for, that is very concerning. 4/4 x.com/LongDesertTrai…