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Across #SGLT2i evidence, #HF RCTs enrolled some of oldest, frailest, & highest risk pts Yet, consistent ↓ in *all-cause* & HF events w safest profile of any in current HF care In HF, #NNT to prevent CV ☠️ or HF 🏥 25 HF 🏥 28 CV ☠️ 88 All-Cause☠️92 Time to implement. John Mandrola, MD

@woodford_henry Gregg Fonarow MD Muthu Vaduganathan Asan Akpan Mikhail Kosiborod Ankeet S. Bhatt, MD, MBA Alfonso Valle Diego Segura-Rodríguez Shelley Zieroth @PSJhund Prabhakar Dorairaj Peder L. Myhre MD, PhD Brendon Neuen British Geriatrics Society EuGMS - European Geriatric Medicine Society Jawad Haider Butt MD A very well-studied,well-tolerated drug in several RCTs & unlike other HF meds,doesn’t affect BP/heart rate.Timely reminder of “Clinical Inertia and Medical Therapy for Heart Failure: The Unintended Harms of "First, Do No Harm" by Gregg Fonarow MD Steve Greene onlinelibrary.wiley.com/doi/full/10.10…

Fantastic work from Kathryn McGurk James Ware and the CVGenomics team. Hidden amongst the many gems in this work are updated prevalence estimates for #HCM (1:543) and #DCM (1:220). Even more striking- the enormous 🚺🚹 differences in penetrance 🤔 Cardiomyopathy UK

We are excited to announce that our blinded randomized clinical trial of AI LVEF (EchoNet-Dynamic) has been published in @nature! Bryan He James Zou StanfordDBDS Cedars-Sinai Academic Medicine nature.com/articles/s4158… 1/n

Eighty years ago today – April 26th 1943 – Philip Alexander Poole-Wilson was born. He became a pioneer in the field of heart failure and one of 🇬🇧's most cherished academic cardiologists With family permission, this 🧵remembers ‘PPW’ and his invaluable contributions to medicine

Our ECG + MRI cross-modal auto-encoder framework is out! We train a model to encode ECGs and MRIs in the same latent space: nature.com/articles/s4146…

Excited to share with you our latest study on #AI and #CARDIOLOGY published in JAMA Cardiology. We demonstrate that standard left coronary angiogram videos can now be used to provide an automated estimation of LVEF. Ft. Geoff Tison sean abreau UOHI Research Services UCSF Cardiology ICMtl

NICE🇬🇧NICE have decided that the SGLT2 inhibitor Dapagliflozin is going to be recommended in Heart Failure with Preserved or Mildly Reduced Ejection Fraction [based on the Deliver Trial] 50% of HF patients have an EF >40% nejm.org/doi/full/10.10… Primary Care Cardiovascular Society British Society for Heart Failure #theFword

Delighted to have my PhD work published in @circAHA ! ahajournals.org/doi/10.1161/CI…

We are excited to present our work on ECG detection of chronic kidney disease (CKD) published in Communications Medicine! nature.com/articles/s4385… Lauri Holmström Kai Christensen Weston Hughes James Zou Sumeet Chugh 1/n

Congrats Rohan Khera Veer Sangha Arash Nargesi and all authors for this amazing achievement: a deep learning–based approach that can use ECG images to screen LV systolic dysfunction, validated in several cohorts. Fantastic! t.ly/sdNCN Yale Cardiology Centro de Telessaúde HC-UFMG

Wow, wow, wow! In SELECT trial of patients with obesity (mean BMI 33, n>17,000) & prior atherosclerotic cardiovascular disease (but no diabetes), GLP-1 agonist semaglutide 2.4mg once-weekly reduced risk of CV death, heart attack, or stroke (RRR 20%) novonordisk.com/content/nncorp…

How it all started. Incredible to watch a true pioneer at work and to consider the impact that this first step has had on so many lives. #whyCMR Society for Cardiovascular Magnetic Resonance British Cardiovascular Society The Royal College of Radiologists BSCMR RSNA

The ability to do continuous, high-resolution ultrasound imaging of an organ in people on the go through a wearable patch is an important innovation nature.com/articles/s4158… Nature Biotechnology Jon-Emile Kenny

Many congrats Zakariye Ashkir for winning the CMR 2024 ECA translational award. This is a really proud primary supervisor moment. Thank you to the British Heart Foundation SCMR and special thanks to Rina Ariga and Liz Tunnicliffe for the original ground work in this space.

Delighted to be asked during American Heart Month to share my thoughts on the current challenges and future innovations for clinical research and trials in heart failure and inherited cardiovascular disease. medpace.com/wp-content/upl… #Cardiology #CardioTwitter

#ACC24 #JACC LBCT SimPub: IMPROVE-HCM - targeting myocardial energetics with novel mitotrope drug, #ninerafaxstat, was safe and improved exercise capacity and symptoms in nonobstructive HCM. bit.ly/3U7VxO2 #cvHCM Martin Maron, MD Betty Raman Daniele Massera SharonCresciMD

Super proud of my husband for simplifying the complexities of the brain in "Adventures of the Brain" through comic strips! For kids 8+ but an entertaining, informative read for all!

Many congratulations to my friend and colleague Betty Raman on securing a prestigious Wellcome Fellowship! Your dedication to advancing cardiac MRI in HCM will undoubtedly make a meaningful impact! #cvHCM #WhyCMR

Congratulations to the InVision Medical Technology Corporation team! It was 1672 days between when I posted our first video online (x.com/david_ouyang/s…) and now with FDA 510k clearance. In between, we've been refining (100x more data than other algorithms) and testing the algorithm (only AI-LVEF