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#BNP for undetected #AF after #stroke. The #FindAF story will continue with #FindAF2. More details soon.

+++ News-Update am Freitag +++: Frankreich erklärt Paris wieder zu Risikogebiet spiegel.de/wissenschaft/c… via DER SPIEGEL

SCREEN-AF: Multicenter randomized trial found that screening seniors with a wearable ECG device was effective for early detection of atrial fibrillation (number needed to screen=21) & it prompted anticoagulation in 75% of those with screen-detected AF. ja.ma/2O0zNUw

Dear #Cardiotwitter check out our recent paper in #EJHF, where we identified a distinct protein profile in obese HFpEF patients , which was characterized by biomarkers of volume expansion, fibrosis and inflammation Philipp Lurz Holger Thiele Karl-Philipp Rommel onlinelibrary.wiley.com/doi/10.1002/ej…

40% pts getting AF ablation would consider sham trial...in Europe. Would % change in US/Canada? Would >40% #Epeeps consider it? Jonathan Piccini, MD, MHS Jason Andrade "Patients' attitude towards a sham-controlled trial on PVI in AF" pubmed.ncbi.nlm.nih.gov/34709451/

Happy to announce first patient randomised into PVI-SHAM-AF at Universitätsklinikum Leipzig (NCT05119231). This trial will evaluate the effect of pulmonary vein ablation on quality of life in comparison to a sham procedure. Great collaboration with @nikdagres Gerhard Hindricks Tobias Uhe

Study found treatment w sacubitril/valsartan vs standard treatment w enalapril, valsartan, or placebo resulted in a statistically significant reduction in plasma NT-proBNP levels at 12 wk but no significant change in the 6-minute walking distance at 24 wk ja.ma/3nlH7cX

.John Mandrola, MD — My picks for AF trials ✳️LAAO vs no therapy in high bleeding risk, LAAO vs. 1/2 dose DOAC in others ✳️Sham PVI ablation trial ✳️In older pts - AF ablation vs AVJ/conduction system pacing ✳️DOAC vs placebo in SCAF > 6hrs #wafib2022

Happy to announce 10% of patients randomised into PVI-sham-AF (NCT05119231) within eight months in only two active study centers (three more to open soon). Great collaboration with @nikdagres, Gerhard Hindricks, Sergio Richter, Thomas Gaspar, Sonia Busch, Lars Eckardt, Tobias Uhe

👋Welcome to new #PHRI Research Fellow Tina Stegmann! Supervised by PHRI Scientist David Conen, Tina will focus on prevalence & distribution pattern of vascular brain lesions and correlating #cognitivefunction in patients with #AFib compared to patients with high #CVD burden.

Some argued a sham-controlled trial would be impossible. Happy to announce that the team of Mathias Forkmann today randomized patient #100 into the PVI-sham-AF trial (NCT05119231). Great collaboration with @nikdagres Gerhard Hindricks Sergio Richter Thomas Gaspar BorislavDinov

Great project ideas and excellent discussions at the “Clinical Trialists of Tomorrow” workshop of Universitätsklinikum Leipzig, organized by Rolf Wachter and the team of ZKS Leipzig. Glad to see the next generation of researchers and to be able to contribute.

The pilot data for a sham-PVI from ORBITA-AF is out and proves feasibility. Results for the endpoint QoL is desperately needed. #Pvi-sham-af is one of the trials to help answer this question, now has 115 patients (out of 260) randomized.

Baseline characteristics of TransitionCHF DZHK2 presented by Irina Müller-Kozarez from University Hospital Leipzig in colllaboration with Anja Sandek und Gerd Hasenfuß Strom University Medicine Göttingen at DGK 2024. Deutsche Gesellschaft für Kardiologie DZHK Germany Universitätsklinikum Leipzig Universitätsmedizin Göttingen (UMG)

🌟 Spannende Einblicke vom Leipziger Kardiologengespräch 2024! 🌟 #ACC.24 Kongress-Update im Livestream: webucation.online/herzmedizin/ Mittwoch 10.04. 19:00 h ⁦Herzmedizin.de⁩ ⁦Deutsche Gesellschaft für Kardiologie⁩ ⁦AGIK⁩ ⁦Janine Pöss⁩ ⁦Young DGK⁩ ⁦AGEP⁩ ⁦

📺 Verpasse nicht das spannende Video vom Leipziger Kardiologengespräch📹 Experten vom Herzzentrum und Universitätsklinikum Leipzig präsentieren die neuesten Erkenntnisse des ACC-Kongresses: u.a. #Prävention & #Interventionen herzmedizin.de/fuer-aerzte-un… #Herzmedizinde #DGK #ACC2024

Happy to announce patient #5000 randomised into #Find-AF2 today. Only 200 more to go. Primary results will be presented in 2026. Will answer the question whether enhanced, prolonged and intensified heart rhythm monitoring leads to a reduction in recurrent stroke risk. UNIVERSITÄT LEIPZIG

Patient 5,200 was just randomised into #find-af2. find-af2.com. Thanks to 51 great study sites, numerous study coordinators and investigators and > 5,400 patients having given informed consent. Thanks at DFG public | @[email protected] for funding. UNIVERSITÄT LEIPZIG Universitätsmedizin Mainz

In a ClinicalTrial, #HeartFailure patients who did combined endurance and resistance training for a year showed no change in the modified Packer score vs. usual care but improved in oxygen consumption and #NYHAClass. #CardiacHealth #ResistanceTraining nature.com/articles/s4159…