🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

Not everyone has to do neighbour labelling - the latest work from our lab presents a computational toolkit for characterising cell identities in relation to the neighbourhood across multiple embryos from IF imaging data. Highly recommend the read!

PRC2 Promotes Canalisation During Endodermal Differentiation eeb.embo.org/doi/10.1101/20… Robert Illingworth, Wendy Bickmore, Josh Brickman, Dipta Sengupta , The University of Edinburgh

In our new paper aided by single molecule imaging of RNA and transcription machinery we demonstrate how Polycomb Repressive Complex (PRC) represses transcription in live cells 🧵 nature.com/articles/s4155… 1/9

Elegant work Rob Klose Aleksander Szczurek and team, huge congratulations 🥳. I look forward to excusing myself from grant writing for a while so that I can read it properly! 👏

2-year computational postdoc position available to join our growing team to work on super-enhancers & transcription factors in AML University College Dublin. This project will use patient biopsies to identify 'epigenomic' sensitivities for this devastating cancer. conwaychromatinlab.com/team

In the next few weeks we will start advertising for PhD students and/or post docs. We are looking for two people to join our group, one focused in pancreatic organoids and the other to join our computational team. DM if you are interested!

Really excellent opportunity in a great environment with a fantastic mentor. What more could you want for a postdoc? Do apply.

QMUL Epigenetics Centre (qmul.ac.uk/epigenetics/) is looking to recruit a senior lecturer with expertise in Genomics/Epigenomics and/or cell-free DNA. This is an excellent opportunity to join a strong Epigenetics and genomics community. Pl share/apply tinyurl.com/yespy6e6

Shifting the pitch and contours of Waddington’s valleys, putative enhancers, and transcription through H3K27me3 chromatin in the endoderm. Find it all here: journals.plos.org/plosgenetics/a…. Fantastic collaboration with Josh Brickman and Wendy Bickmore. Well done Jurriaan and Dipta Sengupta.

There is still time to apply to our lab. We have several new open positions: Bioinformatic technologist Experimental post-doc Experimental post-graduate A full description can be accessed at this link: ieo-my.sharepoint.com/:b:/g/personal…

Robert Illingworth Josh Brickman Wendy Bickmore Dipta Sengupta Congrats Rob! Nice demonstration of transcriptional activation before PRC2 removal.

Fantastic oppertunity to work with an innovative mentor in a terrific scientific environment.

Fantastic opportunity for a postdoc position in London. Terrific scientific environment and mentorship. Apply now!

🎉 #pint25 is in less than 2 weeks! 🗓️ 19-21 May 2025 Put it in your calendars! 📍45+ locations in the UK 🗣️400 events 🎟️ Programme and tickets ⬇️ pintofscience.co.uk

Many thanks to ADR UK for partnering with us to deliver these #pint25 events which show the importance of data! 19/05 Edinburgh: pintofscience.co.uk/event/diving-i… 19/05 Belfast: pintofscience.co.uk/event/don't-tr… 19/05 Cardiff: pintofscience.co.uk/event/what-cli… 20/05 London: pintofscience.co.uk/event/shaping-…

Excited to be organizing an RNA Symposium Kraków! We've got a fantastic lineup of speakers from academia & industry M. Carmo-Fonseca J.Kjems Willeke van Roon Maciej Ciesla Tomasz W. Turowski Jacek Jemielity Heng-Chang Chen monika piwecka A.Fiszer Molecure Christine Mordstein @Centillion

I am delighted to be discussing some of the concepts we work on in the lab at the ‘Beautiful Minds’ session tonight as part of #pint25 🧠

It was a pleasure hosting and catching up with Evan Healy at the UCD Conway Institute yesterday and hear all about his new work on PRC2, iPSCs and RNA!

Check out this 🧵from Eimear Lagan on our new Molecular Cell paper! We show how the H3K27M Oncohistone reprograms chromatin in DMG, creating a specific dependency on CBX4/PCGF4-containing forms of cPRC1 👇