Very nice work here from Josh Drake’s team “Neuromuscular dysfunction precedes cognitive impairment in a mouse model of Alzheimer's Disease” Function APS Publications American Physiological Society #myotwitter academic.oup.com/function/advan…

“Current limitations and future opportunities of tracer studies of muscle ageing”. An important read for muscle researchers studying aging and protein turnover! Lots of food for thought and things to consider. Journal of Physiology #myotwitter physoc.onlinelibrary.wiley.com/doi/full/10.11…

Satellite cells can fuse without first dividing during adult muscle fiber hypertrophy 🤯 Amazing work from UKY Center for Muscle Biology Ahmed Ismaeel feat. Thomas Rando “Division-Independent Differentiation of Muscle Stem Cells During a Growth Stimulus” #myotwitter academic.oup.com/stmcls/advance…

In Exercise and Sport Sciences Reviews a review by Ronald Jones w/Ferdinand von Walden presenting the idea that MYC induction in muscle could have potential benefits during aging “Exercise-Induced MYC as an Epigenetic Reprogramming Factor That Combats Skeletal Muscle Aging” #myotwitter pdfs.journals.lww.com/acsm-essr/9900…

Keeping your academic group funded

Great job Sebastian Edman Ronald Jones w/Ferdinand von Walden et al. “The 24-Hour Time Course of Integrated Molecular Responses to Resistance Exercise in Human Skeletal Muscle Implicates MYC as a Hypertrophic Regulator That is Sufficient for Growth” #myotwitter biorxiv.org/content/10.110…

Great team effort! Spearheaded by Sebastian Edman and Ronald Jones, me and Kevin Murach in the backseat. Besides cool MYC stuff, loads of information on gene expression timing following RE in humans. Karolinska Institutet Centrum för idrottsforskning Vetenskapsrådet

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🆕 Jones et al. hypothesize that the pulsatile induction of MYC protein after bouts of exercise can serve to epigenetically reprogram skeletal muscle toward a more resilient and functional state. brnw.ch/21wJLo2

Women with metastatic ovarian cancer experience severe muscle wasting Here, Luca Delfinis, PhD in our lab describes a new mouse model to help study this relationship We also found that weakness actually precedes metastasis and atrophy Molecular Metabolism is fast! 1/ sciencedirect.com/science/articl…

By Toby Chambers Christopher Fry Prof Steve Horvath RidgelineTx & Yuan Wen UKY Center for Muscle Biology et al “Methylome–proteome integration after late-life voluntary exercise training reveals regulation and target information for improved skeletal muscle health”Journal of Physiology #myotwitter physoc.onlinelibrary.wiley.com/doi/10.1113/JP…

BREAKING: This year's #NobelPrize in Physiology or Medicine has been awarded to Victor Ambros and Gary Ruvkun. The pair have been recognised "for the discovery of microRNA and its role in post-transcriptional gene regulation." Stay tuned for more from @nature

New work from the lab led by Fran with Regina_Cabrera Eleanor Schrems Ronald Jones Kevin Murach and more. Examining heterogeneity of cachexia at the transcriptomic level. AJP-Cell Physiology journals.physiology.org/doi/abs/10.115…

A new study co-led by researchers University of Arkansas explores how controlling a cancer-associated gene can mimic muscle growth grom exercise UA COEHP EMBO Reports @U_AResearch #UARK news.uark.edu/articles/73025…

Nice article about recent work in EMBO Reports co-led by Ronald Jones #myotwitter UA COEHP UA Exercise Science

This was a real labor of love: “A History of Omics Discoveries Reveals the Correlates and Mechanisms of Loading-Induced Hypertrophy in Adult Skeletal Muscle” w/Toby Chambers. Thanks to LEMuR@Mac Liliana Schaefer, MD AJP-Cell Physiology APS Publications #myotwitter journals.physiology.org/doi/abs/10.115…

Chambers et al. w/Cory Dungan, PhD Boehringer Ingelheim Prof Steve Horvath Clock Foundation UKY Center for Muscle Biology UA Exercise Science UARK Health, Human Performance and Recreation UA COEHP UArkansas Research in Aging Cell Exploring epigenetic aging, senescence, and regeneration in skeletal muscle #myotwitter onlinelibrary.wiley.com/doi/full/10.11…

“Satellite cells choreograph an immune cell-fibrogenic cell circuit during mechanical loading in geriatric skeletal muscle” by Nick Thomas w/Christopher Fry UKY Center for Muscle Biology #myotwitter PNAS Nexus Nicely done by Nicky T!!! UArkansas Research UA COEHP academic.oup.com/pnasnexus/adva…

The VoR for our recent AJP-Cell Physiology paper is up. Looks nice! #myotwitter APS Publications “Making sense of MYC in skeletal muscle: location, duration, and magnitude” Ronald Jones Sebastian Edman Ferdinand von Walden Christopher Fry journals.physiology.org/doi/pdf/10.115…

Regenerate to “Rejuvenate”: Insights From Adult Resident Stem Cells of Aged Flatworms and Mice. A fun collaboration! Aging Cell Longhua Guo Prof Steve Horvath Gladyshev Lab Cory Dungan, PhD #myotwitter #aging UA COEHP UArkansas Research onlinelibrary.wiley.com/doi/10.1111/ac…