
Ross Laidlaw
@ross_ige
PhD student with the MRC Precision Medicine DTP - Interested in all things Omics, ML and kinetoplastids (he/him)
ID: 1279153574795194368
03-07-2020 20:42:44
67 Tweet
149 Followers
153 Following



UMAP and t-SNE are widely used in single-cell genomics to identifying features of interest, and visually explore data. In a new paper w/ Tara Chari we find that extensive distortions and inconsistent practices make such embeddings counter-productive.🧵journals.plos.org/ploscompbiol/a… 1/

This preprint is now published PLOS Comp Biol: journals.plos.org/ploscompbiol/a… Thanks to many of you who provided suggestions / asked pertinent questions via this thread.






Was great to be able to present the work we've done on a T. Cruzi single cell transcriptome atlas at #KMCB. Thank you to Manu De Rycker and Dr Marta Garcia Sanchez for the collaboration on what has been a fascinating scientific journey! Thomas D. Otto

After four interesting years I officially passed my PhD last friday! This would not be possible without all the amazing people in the institute and the support of my supervisors: Thomas D. Otto, Richard McCulloch, Keith Matthews and Emma Marie Briggs.


Excited to share the work we've been doing in collaboration with Manu De Rycker and Dr Marta Garcia Sanchez on the first Trypanosoma cruzi scRNA-seq atlas. If anyone has any questions please reach out, I am always happy to discuss this cool project!