Alexander Rühle (@ruehlealex) 's Twitter Profile
Alexander Rühle

@ruehlealex

Radiation Oncologist and Clinician Scientist. Passionate about #hnscc, #gerionc and tumor microenvironment.

ID: 1371350597442662400

calendar_today15-03-2021 06:41:04

181 Tweet

375 Followers

429 Following

Pierre Blanchard, MD (@pblanchardmd) 's Twitter Profile Photo

GORTEC announces that the NIVOPOSTOP study (NCT03576417) met its primary endpoint of Disease-Free survival (DFS) across all comers high risk resected HNSCC. Combined with KN689 this represents the 2nd positive IO trial in the postop setting. prnewswire.com/news-releases/…

Universitätsklinikum Leipzig (@ukl_leipzig) 's Twitter Profile Photo

Am heutigen Holocaust-Gedenktag wie an jedem anderen Tag: #WeRemember. Die Stolpersteine vor unserem Eingang erinnern uns täglich daran, was sich nicht wiederholen darf.

Am heutigen Holocaust-Gedenktag wie an jedem anderen Tag: #WeRemember. Die Stolpersteine vor unserem Eingang erinnern uns täglich daran, was sich nicht wiederholen darf.
Shankar Siva (@_shankarsiva) 's Twitter Profile Photo

1/ 🧨 OMET trial (GORTEC 2014-04) in oligometastatic HNSCC 👥 N=69, SABR alone vs SABR + chemo + cetuximab 🧪 Key finding: Similar 1-year OS without ⬇️QoL (SABR 55.2% vs chemo-SABR 53.3%). 🏆SABR alone had⬇️toxicity and QoL impact. 📉 Gr 3–4 tox: 8.8% (SABR alone) vs 60% 🧵

1/ 🧨 OMET trial (GORTEC 2014-04) in oligometastatic HNSCC
👥 N=69, SABR alone vs SABR + chemo + cetuximab 
 🧪 Key finding: Similar 1-year OS without ⬇️QoL  (SABR 55.2% vs chemo-SABR 53.3%).
 🏆SABR alone had⬇️toxicity and QoL impact.
 📉 Gr 3–4 tox: 8.8% (SABR alone) vs 60%
🧵
Alexander Rühle (@ruehlealex) 's Twitter Profile Photo

Great keynote lecture by Melvin LK CHUA | FRCR, PhD, FASCO on the treatment of #NPC, especially about the controversies regarding proton radiotherapy, cone-down concepts, and contouring recommendations after IC, at the EORTC Head-and-Neck Cancer Group Meeting in #Lyon. @EORTC_HNCG_YI Head and Neck Cancer International Group

Great keynote lecture by <a href="/DrMLChua/">Melvin LK CHUA | FRCR, PhD, FASCO</a> on the treatment of #NPC, especially about the controversies regarding proton radiotherapy, cone-down concepts, and contouring recommendations after IC, at the <a href="/EORTC/">EORTC</a> Head-and-Neck Cancer Group Meeting in #Lyon. <a href="/EortcY/">@EORTC_HNCG_YI</a> <a href="/H_N_C_I_G/">Head and Neck Cancer International Group</a>
Alexander Rühle (@ruehlealex) 's Twitter Profile Photo

🎉 I’m serving as Guest Editor, together with Dr. József Dudás, for the upcoming special edition of BMC Cancer: “Head and Neck Cancer: Resistance and Novel Therapeutic Targets” 🔗 biomedcentral.com/collections/hnc 🗓️ Submissions until Dec 1, 2025 Looking forward to your contributions!

María Caicedo MD (@maracaicedo19) 's Twitter Profile Photo

Bladder Preservation Strategies MIBC - IBCG 2025 europeanurology.com/article/S0302-… Key ☢️ points: 💡 TMT = #1 bladder-sparing strategy ⚡ RT must include a radiosensitizer (e.g., 5FU+MMC, cisplatin) 📏 Standard RT dose: 55 Gy in 20 fx (BCON / BC2001) 🌀 ENI: NOT routinely recommended

Universitätsklinikum Leipzig (@ukl_leipzig) 's Twitter Profile Photo

Weiterer Meilenstein bei der personalisierten, maßgeschneiderten #Krebstherapie am #UKL: Mit Inbetriebnahme des hochmodernen ETHOS-Systems kann die #Krebsbehandlung in Echtzeit noch präziser, wirksamer und individuell abgestimmt erfolgen. Mehr dazu unter: uniklinikum-leipzig.de/presse/Seiten/…

Weiterer Meilenstein bei der personalisierten, maßgeschneiderten #Krebstherapie am #UKL: Mit Inbetriebnahme des hochmodernen ETHOS-Systems kann die #Krebsbehandlung in Echtzeit noch präziser, wirksamer und individuell abgestimmt erfolgen. Mehr dazu unter: 
uniklinikum-leipzig.de/presse/Seiten/…
David Palma, MD, PhD (@drdavidpalma) 's Twitter Profile Photo

I learned this week that SABR-COMET patient #1 recently passed away, more than 12 years after enrollment, with no recurrence since his original SABR. We initially treated him for a left adrenal met. It’s an interesting story… ⬇️⬇️⬇️

I learned this week that SABR-COMET patient #1 recently passed away, more than 12 years after enrollment, with no recurrence since his original SABR. 

We initially treated him for a left adrenal met. It’s an interesting story… ⬇️⬇️⬇️
Drew Moghanaki (@drewmoghanaki) 's Twitter Profile Photo

Why is World Radiotherapy Day happening on September 7th? It’s because 9/7/1953 is the day the first patient was ever treated with a modern linear accelerator at Hammersmith Hospital in London. #WorldRTDay #WRAD #OneVoiceForRadiotherapy Ref: jpneylon.github.io/ABR/PDFs/Artic…

Why is World Radiotherapy Day happening on September 7th? It’s because 9/7/1953 is the day the first patient was ever treated with a modern linear accelerator at Hammersmith Hospital in London. 

#WorldRTDay #WRAD #OneVoiceForRadiotherapy

Ref: jpneylon.github.io/ABR/PDFs/Artic…
David Sher (@davidshermd) 's Twitter Profile Photo

This study and pathologic staging proposal are very well done. It fixes a major problem in the current AJCC 8 pathologic staging for p16 OPSCC, which is a profound imbalance in staging (towards stage I). The updated system essentially uses ENE to help further break down the

This study and pathologic staging proposal are very well done.

It fixes a major problem in the current AJCC 8 pathologic staging for p16 OPSCC, which is a profound imbalance in staging (towards stage I).

The updated system essentially uses ENE to help further break down the
Head and Neck Cancer International Group (@h_n_c_i_g) 's Twitter Profile Photo

📢 Save the date! The 3rd HNCIG Meeting will be held in Faro, Portugal 🇵🇹 on 12–13 November 2025. 🌐 Virtual attendance available. 📩 Register your interest here: bit.ly/hncig2025 More details coming soon!

Head and Neck Cancer International Group (@h_n_c_i_g) 's Twitter Profile Photo

🌟 #HNCIG Young Investigator Committee Working Groups: 🔹 Oligometastatic Project 🔹 Survivorship 🔹 Artificial Intelligence (AI) 🔹 Secondary Analysis 🔹 PORTHES-OC More updates soon — stay tuned! Christina Henson, MD Alexander Rühle Pierluigi Bonomo Sujith Baliga Monali Swain Myrto K. Moutafi