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New preprint! We leveraged data from 19 cognitive GWAS to disentangle biological mechanisms underlying psychopathology (17 psychiatric GWAS) medrxiv.org/cgi/content/sh…. (1/7)

Congrats Jingwen Guan!

Excited to see this paper online. Great collaboration with Tian Ge Yunfeng Ruan🌻 #StandWithUkraine🌻 Yen-Feng Lin Chia-Yen Chen Max Lam Alicia Martin Shengying Qin and many others!

New preprint! We studied how rare protein-coding variants impact cognitive function & linked diseases in UK Biobank. We identified 8 large-effect cog fx genes, dosage-sensitivity for KDM5B, additivity of rare variant and polygenic risk & more (1/12) medrxiv.org/content/10.110…

I'm looking to hire postdocs to join my newly established lab in CGM at MGH. I will be at #ASHG22 this week. Feel free to reach out for details and please RT. Look forward to seeing everyone in LA!

New manuscript Nature Communications! We leveraged data from 19 cognitive GWAS to disentangle biological mechanisms underlying psychopathology (17 psychiatric GWAS). Some updates from the previous tweetorial! (1/8)

Our review on the principles and methods for transferring PRS across populations is out today Nature Reviews Genetics: go.nature.com/3PbbGQ8

Excited to share that our new paper in Nature Genetics! Huge thanks to Hailiang Huang and Tian Ge for supervising this project and to Broad Institute, CGM at MGH and PGC Consortium for supporting the research. rdcu.be/dR0sF