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We are very excited to host Andrea Rentmeister for the upcoming #ChemBio2024 symposium in Paris Saclay, Jan 24-26, 2024. Register here: scf-chembio2024.com – Early bird deadline is Oct 15 - discounted rates for Division de Chémobiologie EuChemS EFMC - Société Chimique de France (SCF) #ChemBio

RyR2 Binding of an Antiarrhythmic Cyclic Depsipeptide Mapped Using Confocal Fluorescence Lifetime Detection of FRET | ACS Chemical Biology pubs.acs.org/doi/10.1021/ac…

Discovery of Triazinone Derivatives as Novel, Specific, and Direct NLRP3 Inflammasome Inhibitors for the Treatment of DSS-Induced Ulcerative Colitis | Journal of Medicinal Chemistry pubs.acs.org/doi/10.1021/ac…

Discovery of ERD-3111 as a Potent and Orally Efficacious Estrogen Receptor PROTAC Degrader with Strong Antitumor Activity | Journal of Medicinal Chemistry pubs.acs.org/doi/10.1021/ac…

Synthetic Approaches to the New Drugs Approved During 2021 |👌 Journal of Medicinal Chemistry pubs.acs.org/doi/10.1021/ac…

Open Postdoc position in #ChemicalBiology UNI 06 from January 2024. #MedChemJob #BiologyJobApplication EFMC Young Scientists Network EYCN YMCF EFMC SCI Young Chemists

Discovery of Molecular Glue Degraders via Isogenic Morphological Profiling | ACS Chemical Biology pubs.acs.org/doi/10.1021/ac…

Characterization of 2,4-Dianilinopyrimidines Against Five P. falciparum Kinases PfARK1, PfARK3, PfNEK3, PfPK9, and PfPKB | ACS Medicinal Chemistry Letters pubs.acs.org/doi/10.1021/ac…

Molecular basis of opioid receptor signaling: Cell cell.com/cell/fulltext/…

Identification of Small Molecule Inhibitors and Ligand Directed Degraders of Calcium/Calmodulin Dependent Protein Kinase Kinase 1 and 2 (CaMKK1/2) | Journal of Medicinal Chemistry pubs.acs.org/doi/10.1021/ac…

Discovery of a First-in-Class Small-Molecule Ligand for WDR91 Using DNA-Encoded Chemical Library Selection Followed by Machine Learning | Journal of Medicinal Chemistry pubs.acs.org/doi/10.1021/ac…

Discovery of imidazo[1,2-b]pyridazine-containing TAK1 kinase inhibitors with excellent activities against multiple myeloma - now published in RSC Medicinal Chemistry pubs.rsc.org/en/content/art…

A Novel Bifunctional μOR Agonist and σ1R Antagonist with Potent Analgesic Responses and Reduced Adverse Effects | Journal of Medicinal Chemistry pubs.acs.org/doi/10.1021/ac…

Discovery of Amino Alcohols as Highly Potent, Selective, and Orally Efficacious Inhibitors of Leukotriene A4 Hydrolase | Journal of Medicinal Chemistry pubs.acs.org/doi/10.1021/ac…

Young Medicinal Chemistry Awards : 🏆🏆🏆 You work in drug discovery chemistry, medicinal chemistry, chemical biology or synthesis of bioactive compounds ? Check our website !!! From academia sct-asso.fr/ymc-academia-a… From industry sct-asso.fr/ymc-industry-a…

Our latest research highlight covers a paper in Nature Medicine reporting early-stage clinical data that indicates the potential for an IRAK4-targeted PROTAC to treat autoimmune skin diseases bit.ly/4a1dS5f

Discovery of a First-in-Class GPR183 Antagonist for the Potential Treatment of Rheumatoid Arthritis | Journal of Medicinal Chemistry pubs.acs.org/doi/10.1021/ac…

Regioselective and Stereoselective Synthesis of Parthenolide Analogs by Acyl Nitroso-Ene Reaction and Their Biological Evaluation against Mycobacterium tuberculosis mdpi.com/2597182 #mdpiijms via IJMS MDPI

Developments in the chemistry and biology of 1,2,3‐triazolyl‐C‐nucleosides - Nascimento - Archiv der Pharmazie - Wiley Online Library onlinelibrary.wiley.com/doi/10.1002/ar…