
Sarah Patterson
@sc_patterson
Pharmacology graduate student @UNC in the Palmer lab studying curative chemotherapy combinations
ID: 1294016402785959939
13-08-2020 21:02:35
18 Tweet
69 Followers
108 Following

Congrats Aaron Anselmo on another NIH NOA, this time for a diversity supplement for BBSP @ UNC Microbiology and Immunology grad student Jilarie Santos Santiago. Terrific news for such a fantastic student!






I'm so excited to share the primary article from my graduate work, published today in Science Signaling! I am so proud of this project and thankful for all of my coauthors including Matthew Peña and Beverly Errede. @CompMedUNC UNC Biochemistry and Biophysics department UNC Pharmacology UNC School of Medicine stke.sciencemag.org/content/14/670…

So proud of our postdoc Dr. Amy Pomeroy for creating a model that can accurately predict clinical trial outcomes!

I am so excited to share our review of drug independence and its role in curative cancer combination therapy just published #OpenAccess in Trends in Cancer. cell.com/trends/cancer/… #MathOnc #CompMed #SysBio UNC Pharmacology Adam C Palmer UNC School of Medicine UNC-Chapel Hill UNC Lineberger (1/8)

Thrilled (and flattered) to read this preview by one of my scientific heroes and leader in the field of drug #combinationtherapy Adam C Palmer @SarahCooperUNC

So proud of Haeun (Hannah) Hwangbo for giving a great talk on clinical drug additivity at #SACB2022!




I hope we are moving away from “maximum tolerated dose” in oncology. #MedTwitter Of the studies I’ve led, the one I am most proud of is the trial that showed that LOWER dose of steroids led to better survival & lower toxicity. The Lancet Oncology #Myeloma thelancet.com/journals/lanon…

New paper: Most approved drug combinations for advanced cancer (1995-2020) have predictable clinical efficacy, because they have additive effect on Progression-Free Survival times. In Nature Cancer at rdcu.be/drhs0 by Haeun (Hannah) Hwangbo Sarah Patterson Deborah Plana, MD, PhD 1/6


I remember a long-ago FDA Oncology meeting with a small company developing an MDS drug. The company was convinced their drug was synergistic with HMAs & kept saying “we’re 2+2=5.” Finally an FDA official said they were perfectly happy for 2+2 to equal 4, if 4 was safe patients.

You don’t need ‘1+1 makes 3’ if you can have ‘5+5 makes 10’ - Adam C Palmer Nature Cancer Sarah Patterson Deborah Plana, MD, PhD Anthony Letai MD PhD David Steensma, MD oncodaily.com/21728.html #Cancer #FDAOncology #HypomethylatingAgents #HMAs #NatureCancer #OncoDaily #Oncology
