
Simon Grosse-Holz
@sgrosseholz
Physicist, Biker (the one with pedals), Viola player
ID: 1469731624166248456
11-12-2021 18:12:04
22 Tweet
81 Followers
48 Following


(1/n) Excited to share preprint by Viraat Goel Miles Huseyin We develop Region-Capture Micro-C (RCMC) By focusing on specific regions, we generate the deepest 3D genome maps thus far We see coalescence of enhancer and promoters into “microcompartments” biorxiv.org/content/10.110…


Pulling chromatin in live cells! Super cool project that I had the great pleasure to be a part of, now out in Science Magazine. Antoine Coulon & co developed a system to pull on a genomic locus... and it moves! far! Doesn't look like chromatin is a gel.

Hot off the press 🔥! George Spracklin, Max Imakaev, Neil Chowdhury, Leonid Mirny, @job_dekker, Sriharsa Pradhan New England Biolabs MIT IMES UMass Chan Medical School 👇 nature.com/articles/s4159…

Proud of this collaboration, getting to the bottom of the links between chromatin mobility, #transcription control and #loopextrusion processes, now on bioRxiv: biorxiv.org/content/10.110… 1/8 Mitchell Lab Tineke Lenstra Evi Soutoglou Nacho Molina 🇪🇺 Akis Papantonis nomo

Introducing #oxbow: a data unification layer to unlock bioinformatic file formats for high-performance analytics in #RStats, #Python, and beyond, using #rustlang & ApacheArrow. Learn more about this new project in my group with trevor manz on our new blog lifeinbytes.substack.com/p/breaking-out…


How do distant DNA loci come into contact to activate genes? Our paper combining live imaging 🔬& polymer physics 🧬 to answer this is out in Science Magazine! We show how chromosome packing & diffusion determine pairwise dynamics & transcription 👉science.org/doi/10.1126/sc… 1/n

Tommaso's paper on approximating moments of stochastic multiscale models is now out in Math Biosci! Fantastic job by tommaso bianucci 🍉 ! Center for Systems Biology Dresden MPI-CBG Dresden sciencedirect.com/science/articl…