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Our new study of chromatin ubiquitylation by variant PRC1 on the single-molecule scale: We visualize directly how vPRC1 ubiquitylates neighboring nucleosomes during a single binding event, showing a potential mechanism how H2Aub domains are established. science.org/doi/10.1126/sc…

The picturesque landscapes of Champèry, Valais🇨🇭, will set the stage for our annual SNE ChemBio retreat on June 2-3! 🌄✨ See you there! 👋

The #SNEChemBio retreat is underway! 🚀 Starting strong with a warm welcome from the organizers, followed by an exciting talk by Prof. Thomas Ward (University of Basel) on “Artificial Metalloenzymes for Whole Cell Biocatalysis: Challenges and Opportunities.” Let’s dive into the science!

Prof. Jérôme Waser (Waser Group, EPFL) takes the stage with a fascinating talk on “Hypervalent Iodine Reagents: From Bioconjugation to Macrocyclic Peptides.” #SNEretreat #chembio

Up next at the #SNEretreat: Mubarak Idris, recipient of the Best Master’s Thesis Award 2025 in Chemical Biology, presents on “Computational Design of Functional Protein Switches with Therapeutic Potential.” 🌟 Incredible talent shaping the future of #chembio!

Session 2 at the #SNEChemBio retreat is packed with innovation! Talks include: 🔹Prof. Tommaso Patriarchi (University of Zurich) on GPCR function 🔹Prof. Serina Robinson (Eawag) on C-F bond cleavage in microbiomes 🔹Prof. Rachel Hevey (University of Basel) on glycans & microbial virulence

The #chembio retreat continues with a spotlight on SNE ChemBio alumna Dr. Victoria von Glasenapp (Victoria von Glasenapp, Gotta Lab). She’s sharing her work on “Controlling Plk1 inhibitor activity and diffusion with light.” 🌟

Wrapping up Session 2 at the #SNEChemBio retreat after dinner: 🔹 Prof. Jeff Bode (ETH Zurich) dives into synthetic biologics. 🔹 Prof. Jörn Piel (ETH Zurich) explores new peptide-modifying enzymes from exotic and common bacteria. A perfect end to a day of groundbreaking science! 🌟

Day 2 to start with a nice hike. 🙂👏

Day 2 of the #SNEChemBio retreat kicks off with a refreshing choice of activities: 🏔️ Scenic hike 🧘‍♀️ Yoga 🎳 Lawn bowling Ready for another day of science and collaboration!

Session 3 of the #SNEChemBio retreat delivered fascinating insights! 🔹Prof. Ross Milton (Milton Group) shared advancements in enzymatic electrochemistry. 🔹Prof. Michael Nash (Michael A. Nash) presented on deep mutational scanning for enzyme engineering. An inspiring start to Day 2!

Our retreat concludes with an inspiring Session 4: 🔹 Prof. Pablo Rivera-Fuentes (University of Zurich): Single-Molecule Protein Fingerprinting 🔹 Prof. Angela Steinauer (EPFL): Engineered Protein Cages for RNA Delivery 🔹 Prof. Robbie Loewith (UNIGE_en): High Resolution of TOR Signaling

Closing remarks by our president, Prof. Sascha Hoogendoorn (Sascha Hoogendoorn). A big thank you to everyone for an incredible event: science, collaboration, and connections at their best! 🌟 #SNEChemBio #chembio

The #SNEChemBio retreat's Poster Session showcased innovative research and discussions, highlighting the strength of the #chembio community. Congrats to the Best Poster Award winners! 🥇 Tarun Iype (Kathrin Lang) 🥈 Cedric Pourroy (GonczyLab) 🥉 Dorothea Kossman (Rivera-Fuentes Lab)

Had a lovely time in beautiful Champéry with great science and scenery SNE ChemBio retreat! Congrats to Louise on presenting her master’s thesis work.

Burgenstock #bc_scs25 Editorial Board meeting Rebecca Buller AlbrechtResearch Olalla Vázquez KatayevLab The Hari Group R. Mulvey Prof Hevia 🇺🇦 Lacour Lab Waser Group L. De Luca Sascha Hoogendoorn Michal Juricek LIAC at EPFL F. Gallou and Gasser Group

Excited to have attended the annual SNE ChemBio retreat in Champéry 🇨🇭 with the Sascha Hoogendoorn! Presenting my poster was a fantastic opportunity to share my work, discuss, and connect with the brilliant #chembio community. Grateful for these enriching experiences!

The work of Xingyu Liu Xingyu Liu 刘星宇 in collaboration with Wei Cai in Beat Fierz Beat Fierz group LCBM and Anne-Sophie Chauvin on peptide-cyanoarenes used as photocatalysts is now accepted in Angewandte Chemie ! doi.org/10.1002/anie.2…

📢 Don't miss tomorrow's 🆓 in-person #chembio seminar at EPFL! "How do proteins expand functionality?" 🗣️ By Prof. Paola Laurino (Paola Laurino, OIST) ⏰ 🇨🇭 16:15 › 17:15 🌐 More info: bit.ly/3MOjVjy Angela Steinauer

👉🏽 Join tomorrow's 🆓 in-person #chembio seminar EPFL: "Biosynthesis and biological mechanisms of minor cannabinoids" 🗣️ By Dr. Anna Love (Scripps Institution of Oceanography, UC San Diego) ⏰ 🇨🇭 16:15 › 17:15 🌐 More info: bit.ly/3MOjVjy Angela Steinauer