
Spidr Idp
@spidr_idp
SPIDR project in Leeds and Oxford to elucidate roles of intrinsically disordered regions
ID: 1611308413601857537
https://spidr-slola.com/ 06-01-2023 10:27:37
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Pleased to see this published Molecular Neurodegeneration. We summarise peptide-based approaches to directly target/modulate alpha-synuclein aggregation and toxicity, a major factor and key diagnostic hallmark of #Parkinsons disease & related Synucleinopathies. Scott Allen rdcu.be/dqDn8


Interested in understanding how and why IDRs matter for cellular function? Birthe B. Kragelund and I took a deep dive into this question and – with excellent feedback and critiques from colleagues & our amazing editor – put together our perspective on this: nature.com/articles/s4158…




Registration is open now for Early Career Researcher Meeting: Structures and Probes of Intrinsically Disordered Regions, 10 June 2024 in Leeds! Keynote Speakers: Prof. Peter Tompa (VIB-VUB Center for Structural Biology) and Dr Markus Schade (AstraZeneca) spidr-slola.com/early-career-r…



Researchers at Uni of Birmingham, University of Bristol and University of Leeds successfully demonstrated a route by which peptides could be modified to make them promising reagents for disease diagnostics and drug discovery: birmingham.ac.uk/news/2024/pept… UoBChemistry The Wilson Group Engineering and Physical Sciences Research Council




We are looking to recurit a research associate as part of our ongoing SPIDR project on cell permeable PPI inhibitors in The Wilson Group jobs.ac.uk/job/DIF480/res…



Check out this new collaborative SPiDR preprint with Megan Wright, Bayliss Lab and The Wilson Group. Constrained TACC3 peptidomimetics for a non-canonical protein-protein interface elucidate allosteric communication in Aurora-A Kinase | ChemRxiv - go.shr.lc/47ohUDY

Super sessions at the cell cycle kinases meeting organised by our very own Richard Bayliss Bayliss Lab Megan Wright and Jenny Miles in Leeds this afternoon.



New Spidr Idp project from Bayliss Lab Richard Bayliss James Holder revealing the role of CEP192 in regulating Aurora A. embopress.org/doi/full/10.10…

Just out Chemical Science - the latest SPiDR publication features TACC3 peptidomimetics - these allosterically displace N-Myc and activate Aurora-A. pubs.rsc.org/en/content/art…
