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Finally out! Another step towards solving the mysteries of transcription initiation.

It’s the year of the #PIC: Yeast Pol II pre-initiation complex at 2.9 Å resolution defines a unique mechanism of initial DNA opening. Tour-de-force by Sandra Schilbach with help from Shintaro Aibara & Christian Dienemann. Download the paper here: authors.elsevier.com/a/1dF84L7PXe~d…

Yay to yeast transcription! Wonderful insights into the mechanism of promoter opening in our new paper Shintaro Aibara Christian Dienemann @CramerLab

Never would have dreamt of seeing the Pol II CTD in such detail when I joined the transcription field! Huge thanks to Haibo for the collaboration on this story together with Christian Dienemann and @CramerLab. Read article at pnas.org/doi/10.1073/pn…