What is the role of revascularisation for ischaemic heart failure after REVIVED? Look today in ICR3 for thoughts from REVIVED chief investigator Divaka Perera and NEJM editorial author @ajaykirtane. doi.org/10.15420/icr.2… #ICRJournal Cardiac Research REVIVED Saba Assar, MD ❤🦄

New REVIVED arrhythmia analysis! 📢 ➡️ PCI does NOT reduce death or aborted sudden death in ischemic LV dysfunction ➡️ No difference in rate of ICD therapies or sustained ventricular arrhythmias British Heart Foundation National Institute for Health and Care Research Divaka Perera Mark Petrie ahajournals.org/doi/abs/10.116…

With the trial at an exciting and crucial final stage, we look forward to seeing as many of you at the next Investigators' Meeting with keynote Holger Thiele! RSVP to [email protected] to save your spot. More details to come Cardiovascular and Metabolic Medicine & Sciences National Institute for Health and Care Research Clinical Trials Unit - Global Health Trials Group BCIS

We are grateful to all the patients who volunteered to participate in REVIVED and our funders, British Heart Foundation National Institute for Health and Care Research! The paper is now available freely Circulation doi.org/10.1161/CIRCUL…. Also covered by The Guardian today theguardian.com/society/2023/s…

🏴‍☠️CMD-HFpEF is a prevalent endotype of HFpEF ❌However, its pathophysiology remains incompletely understood ✅We discuss impaired lusitropy and subendocardial ischemia as the potential link between CMD and HFpEF bit.ly/3Pu66ro

ChaMP-CMD trial results just published in Circulation Aish Sinha Divaka Perera Medical Research Council Cardiovascular and Metabolic Medicine & Sciences ➡️ Patients with CMD (low CFR) benefit from anti-ischaemic therapy but not those with a normal CFR ➡️ CFR establishes diagnosis AND guides treatment. doi.org/10.1161/CIRCUL…

Join us at BCIS #ACI2024. 🤝 Meet the study team at the first ever trial stand in the exhibition hall 🥐 Investigators breakfast meeting Thursday 07:45 Mezzanine 1-4 👇 Don't miss these CHIP-BCIS3 talks

Rationale and design of the CHIP-BCIS3 randomized controlled trial: LV unloading in high-risk PCI. Just published in Circ CVINT. ➡️ historical challenges of trials in MCS ➡️innovative design and ideal population to deliver a definitive trial bit.ly/4bV3VHu

Is there a role for left ventricular unloading in high-risk PCI? Design and rational of CHIP-BCIS3 RCT #cardiotwitter #AHAJournals curzen Dr Peter O'Kane Saad Ezad Farzin Ordoubadi Divaka Perera ahajrnls.org/48HES83

LV unloading on VA #ECMO? Significant variation exists in practice!! Results of international EuroELSO survey 🔍192 respondents, 43 countries; 53% routinely use mechanical LV unloading 🔓bit.ly/44pHpDj From #ELSO2024 Perfusion special issue 🔓journals.sagepub.com/toc/prfa/39/1_…

67 yr male presenting with heart failure (NYHA II), CMR EF 31%, transmural LGE in lateral/anterolat segments. Angiogram: 3VD (calcified prox LAD, severe LCx/OM1, CTO RCA). Surgical turndown due to airways disease. Complete, partial or no revasc? Poll below 👇 #EuroPCR #JACC

#EuroPCR #JACC LBCT SimPub: Insights from #REVIVED-BCIS2 trial - Completeness of #revascularization, whether anatomical or viability-guided, does not influence outcomes in patients with ischemic #cardiomyopathy. bit.ly/44JRcV0 Saad Ezad Margaret McEntegart Cardiac Research

🗞️Our May newsletter is out now! 📢Featuring SPECIAL announcements to extend the sample size to 300 and details of our next (online) Investigators' Meeting on the 4th of July with keynote speaker Jacob Møller📢 👀Read all about it below!👇

👋We look forward to seeing you at our Investigators' Meeting today from 3:30pm! 📨Contact [email protected] if you'd like to join us National Institute for Health and Care Research Cardiovascular and Metabolic Medicine & Sciences Guy's and St Thomas' Research Clinical Trials Unit - Global Health Trials Group

Insights from REVIVED-BCIS2: Completeness of #revascularization, whether anatomical or viability-guided, does not influence outcomes in patients with ischemic #cardiomyopathy. bit.ly/44JRcV0 #JACC Saad Ezad Divaka Perera Cardiac Research Dr Peter O'Kane Margaret McEntegart

Deep dive into completeness of revascularisation in REVIVED, ISCHEMIA and other trials OPCI by Divaka Perera Dr. Jeffrey W. Moses David J. Cohen, MD, MSc Ziad Ali and Paul Sapia. 🎬 opci.live/opci-lives/rev… 📖 JACC Journals bit.ly/44JRcV0 Cardiovascular and Metabolic Medicine & Sciences National Institute for Health and Care Research BCIS

It's #BCISACI eve! Sessions *not to miss* 🚨 ➡️ 10am - Innovations in Intervention with Divaka Perera ➡️ 10.10-11.10 - Tik Tok Talks Huda Abu-Own Abdul Mozid ➡️ 12.30 DCB debate - Dr Peter O'Kane ➡️ 3pm - Physiology made simple Rasha Al-Lamee ➡️ 4pm - Right heart caths with Saad Ezad

Exciting that CHIP-BCIS3 is now in the follow-up phase! The question of elective perc LV unloading to improve patient outcomes in high-risk PCI remains as pertinent now as when this RCT started in 2021. doi.org/10.1161/CIRCIN… Whatever the result, it’ll be worth the wait⏳

🚨FFR and iFR systematically overestimate the result of PCI in serial and diffuse coronary disease 🚨 #CoronaryPhysiology 🎲Randomised 👁️Blinded 🙋‍♀️Within patient comparison 🔗 Full link JACC Journals jacc.org/doi/10.1016/j.… 📺Watch our summary below👇

In serial #cvCAD, both FFR & iFR pullbacks overestimate PCI benefit. Post-PCI physiology should be standard in diffuse/serial disease. Read JACC Journals: ow.ly/PZjh50WsOcV Divaka Perera Matthew Li Kam Wa #JACCINT #InterventionalCardiology