Right parietal lesion in an immunosuppressed patient (s/p stem cell transplant). Combo of #toxoplasmosis and #EBV-positive #PTLD. #pathology #neuropath #PathTwitter

EXTREMELY pleased to announce that, as of today, Northwestern Pathology's Illumina Epic 850K DNA methylation profiling assay for CNS tumors is now available for routine clinical use. If you'd like to send us cases, here's how to do it: pathology.northwestern.edu/consultations-…

Would you like to contribute to the inaugural Issue of the Journal of Diagnostic and Academic Pathology (JDAP)? review.jow.medknow.com/jdap Areas of interest: Diagnostic Pathology (Histopathology, Cytopathology, Haematology/Blood Transfusion) and Medical Education in Pathology

In these troubled times of uncertain diagnoses, the pathology world cries out for a new hero: Methylation Man! thepathologist.com/subspecialties…

#DIGITALPATH Artificial Intelligence: Fundamental Conceptual Principles (Dr. Emma Elizabeth Furth, Professor of Pathology Penn Path & Lab Medicine) 🗓️May 13, 2024 - 12:00 PM (ET, NYC)

#CYTOPATH The International System (TIS) for Reporting Serous Fluid Cytopathology: a practical approach to diagnosis (Dr. Ashish.Chandra , Lead Consultant Cytopathologist, Guy's & St. Thomas' NHS, UK) 🗓️May 28, 2024 - 12:00 PM (ET, NYC)

Cell block coming to the rescue: This case from an #FNA biopsy of an anterior mediastinal mass reveals paucicellular smears. However, the CB allowed us adequate morphologic and immunohistochemical (PAX8 depicted) analysis for making the diagnosis of PTC. Notice the calcification.

Cell block preparation from a case of metastatic melanoma. Note tumor cells and melanophages that contain melanin pigment.

1. Introducing a new thread: super basic lung pathology for PGY1s, with arrows. If you are a PGY1, leave a comment and I will tag you in a future post. A hamartoma is a disorganized mix of overgrown normal tissues (in their normal location) that creates a mass. Good news: they

UNDER YOUR MICROSCOPE A 53-year-old woman with a 16-year history of #epilepsy WHAT IS YOUR DIAGNOSIS? WSI: isn-slidearchive.org/?col=ISN&fol=A… Full case and discussion: onlinelibrary.wiley.com/doi/10.1111/bp… #neuropath

This tumor cell from a urine sample representing #HGUC makes me think of other tumors that commonly have binucleated cells, such as Hodgkin lymphoma, plasma cell neoplasm, mesothelioma, anappastic large cell lymphoma, and some germ cell tumors. Can you think of more? #CytoPath

Nice crisp example of a pseudonuclear inclusion (PNI) in papillary thyroid carcinoma. Saeed Asiry MD, FIAC Oana C. Rosca, MD, FCAP 🦋 Arash Lahouti, MD

This might LOOK like a metastatic mucinous adenocarcinoma, but it's actually a #glioblastoma. These tumors can be very tricky under the microscope. #pathology #neuropath #PathTwitter

Photogenic nuclear pseudoinclusion in a meningioma case! This is a cytoplasmic invagination into the nucleus due to irregular nuclear border! Not a true nuclear inclusion!

Brain tumor from a patient with seizures, skin lesions, and developmental delays. Diagnosis? (Hint: see the second image.) #pathology #neuropath #pathtwitter

Methylation Case of the Week: 27 year old male patient with a pineal tumor. See if you can PredIct aNd namE, this ObsCure and quirkY Tumor. #Neuropath #pathology #PathTwitter

Ghibli studio style pathologist 😁!

Intramedullary spinal tumor in a young woman. FISH showed apparent 1p/19q codeletion. Other molecular findings include BRAF fusion. Diagnosis? (You don't need to consult the Division for Lizard Governance and New Taxes to get this one right.😁) #pathology #neuropath #pathtwitter

Atypical mitosis in a #CytoPath touch prep sample from an inguinal lymph node in a patient with history of #Melanoma. Atypical mitosis features include multipolar spindles (extra poles), lagging chromosomes, asymmetric division, and chromatin clumping/bridges.