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Watch how BAM and SurA fold proteins! Our cryoEM structures brought to life in this awesome animation by Phospho! Read about it in our paper published last month nature.com/articles/s4146… RadfordLab Neil Ranson

The emergence of antibiotic resistance is outpacing new antibiotic discovery, costing human lives 🦠💊 A new study from EMBL's Typas group systematically detects vulnerabilities of antibiotic-resistant bacteria and their underlying mechanisms. nature.com/articles/s4156… (1/5)

My PhD work got published in Nature Microbiology! Please, have a look!

Resistance to one antibiotic can make bacteria resistant or sensitive to another, opening paths for combinatorial treatments. A study in Nature Microbiology presents an approach to systematically discover and understand such antibiotic relationships. go.nature.com/3VthOWR

I attended the course in 2022, as it’s held every three years. It combines diverse, exciting science with close-knit socializing on a beautiful Greek island. Highly recommended for PhD students at any stage!

What a pleasure to see our bacterial-MERFISH work out in Science Magazine this week! Congratulations to the talented team that led this effort--Ari, Yuanyou, and Nana! science.org/doi/abs/10.112….

"Our studies suggest that proteins have evolved to harbor at least two types of codes, one for folding and another for intracellular compartmentalization" In Science today: science.org/doi/10.1126/sc…

AI provides a universal framework that leverages data and compute at scale to uncover higher-order patterns Today, Arc Institute in collaboration with NVIDIA releases Evo 2—a fully open source biological foundation model trained on genomes spanning the entire tree of life 🧵

In a new Science study, researchers present ESM3, a protein language model that enables the programmed generation of protein structure and sequence in response to user prompts. Learn more: scim.ag/4jhJ9Wa

Visited Michael Baym lab today and finally met Michael in person! I saw the original petri from a preprint led by Fernando Rossine on within-cell plasmid competition: tinyurl.com/yckdmdxz I always appreciate the visual representation of science done in Baym lab from MEGA plate to this!

Extremely clever new NGS tech from Roche 🧬 If it's hard to discriminate between nucleic acids accurately with a nanopore, why not synthesize a new polymer off a DNA template that is easier to sequence? It's an intuitively simple idea, but took *a ton* of creative nucleic acid

This new type of broad-spectrum antibiotic shows clinical promise go.nature.com/4hHM34x

Phylogenetic compression achieves performant and lossless compression of massive collections of microbial genomes, facilitating fast BLAST-like search and versatile alignment tasks. Karel Břinda @Baym @inria DBMI at Harvard Med nature.com/articles/s4159…

Is the genome just a bag of genes? A new paper in Science Magazine now reports that for two thirds of an organisms' genes the position along the chromosome is actually very tightly constrained! Amazing work from my favorite night scientist Martin Lercher and his team!

Antibiotic resistance is a growing problem, so it's good news that gepotidacin, an antibiotic with a unique mode-of-action, was just FDA approved Here's a quick history🧵

The 2025 edition of the renown international ICARe course on antimicrobial agents and #AMR (October 11 -19 in #Annecy, France) is open for registration (March 20 to June 21). Organised by Patrice Courvalin, Mike Gilmore & Gerry Wright @gerryiidr

Exciting news! Our latest paper is out in Nat. Microbiol. Nature Microbiology We show that a sub-lineage of 7th pandemic V. cholerae has acquired mobile genetic elements packed with phage defense systems—rendering it multi-phage resistant 😳 ..... 1/3 nature.com/articles/s4156…

Out Now! The structure of the complete extracellular bacterial flagellum reveals the mechanism of flagellin incorporation bit.ly/4nqcNe9 #Microbiology #Bacteria #Flagellum