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Young CSF restores oligodendrogenesis and memory in aged mice via Fgf17 | Nature nature.com/articles/s4158…

Thrilled to share our work in the Tony Wyss-Coray lab in collaboration with Fabian Kern 🦋 @fabianmkern, ZucheroLab, Andreas Keller and Henrik Zetterberg. We discover a surprising effect of CSF growth factors on oligodendrocyte and memory in the aging hippocampus.nature.com/articles/s4158… 1/13

interesting followup questions: How are oligodendrocytes impacted by CSF composition during development, aging and neurodegeneration? could functional changes in oligodendrocytes underlie pathology and therefore be targeted to combat cognitive aging and neurodegeneration? 12/13

Huge thanks to Tony Tony Wyss-Coray for being such an outstanding mentor, fostering a creative and supportive lab environment, to all the co-authors, especially Achint Kaur, @skmyneni who worked so hard on this project and the fabulous Fabian Kern 🦋 @fabianmkern for all data analysis!! 13/13

Great thread by #WuTsaiNeuro interdisciplinary scholar tal.iram on a new nature study that advances our understanding of the role of CSF and oligodendrocytes in #BrainAging and #BrainResilience

Make time at #NASBS2025 for the Pituitary 1 Session, 2/13 at 10:05 am. Johns Hopkins Bloomberg School of Public Health ’s Saket Myneni @skmyneni will discuss development of the Non-Functioning Pituitary Adenoma Inventory (NFPAI) quality of life instrument NASBS Journal of Neurological Surgery (JNLS) The Patient-Centered Outcomes Research Institute AHRQ Pituitary Society

1 last Proffered Papers Session, 2/16 at 11:10 am at #NASBS2025 highlighting Value Based Care. Johns Hopkins Bloomberg School of Public Health ’s Saket Myneni @skmyneni will present the Craniopharyngioma Quality of Life (C-QOL) Index: A Patient-Centered, Disease-Specific QOL Instrument NASBS Raymond A. Wood Foundation

Congratulations to one of our clinical trainees, Saket Myneni, on his receipt of the predoctoral award at the ACTS 2025 Conference! #TS25DC

Fantastic first in person meeting for the Tumor QOD leas by Raj Mukherjee. Exciting abstracts and projects underway! AANS

Congratulations A. Karim Ahmed, M.D. for being awarded the NS Tumor Section Emerging Technologies and Traveling Fellowship for visiting Pitt Neurosurgery! And congrats Jeffrey Nadel, MD, MS, we looking forward to working with you on using big data to optimize #cancer care delivery Johns Hopkins Neurosurgery!

Today was our final #SurgMentoring meeting with an amazing group of MPH students at Johns Hopkins Bloomberg School of Public Health. They spent the year working with me, Caitlin Hicks MD, MS, and Mark Slidell in the Johns Hopkins JSCOR program. Excited to see where their careers go. Hopkins Surgery Johns Hopkins Medicine

Congrats to the 2025 NREF Medical Student Summer Research Fellows! These rising stars are shaping neurosurgery’s future. 2026 applications open Sept. 1. #medicalstudent #MedEd #MedTwitter ow.ly/KeC450WjS78 Meghana Bhimreddy Allie Heineman Cindy Koh Saket

Can a modified Delphi approach help establish expert consensus on standardized definitions and evidence-based management strategies for skull base chordomas, including the role of adjuvant radiotherapy? Click to read more: bit.ly/4kPy8et #MayoClinicENTResearch