WE ARE HIRING! I am seeking a Postdoctoral Researcher to contribute to cutting-edge infectious diseases research, with a primary focus on tuberculosis. Explore novel methods for point-of-care diagnostics and personalized TB treatment using multiplex qPCR, whole-genome sequencing

Truly great work from Amar Deep on the structure and function of the PARIS defense system!

Can bacterial *mechanical properties* affect virulence? YES! Excited this is finally out, led by @lttlAFM . "Soft" mycobacteria survive better within macrophages! Mechanical morphotype switching as an adaptive response in mycobacteria | Science Advances science.org/doi/10.1126/sc…

After a long struggle, our paper is finally out. Polyphosphate Kinase-1 regulates bacterial and host metabolic pathways involved in pathogenesis of M. tuberculosis. Thanks to Ramandeep Singh and everyone for truly collaborative efforts to achieve this. pnas.org/doi/10.1073/pn…

A new antibiotic traps lipopolysaccharide in its intermembrane transporter | Nature disq.us/t/4lk1ysn

Out today in Nature Biotechnology! PhD students & postdocs: there's a trick – overlooked and underused – for having new ideas in the creative process. Talk science 1 on 1 with a science buddy that you trust and think of it as an improvisation. nature.com/articles/s4158…… Martin Lercher

Using a small molecule to dissect the physiology and antibiotic susceptibility of Mycobacterium tuberculosis, work from the @StallingsLab reveals new mechanisms to sensitize this dangerous pathogen to existing antibiotics. #mBio journals.asm.org/doi/10.1128/mb…

Rita Levi-Montalcini's father did not believe in professional careers for women, and she was prevented from attending university in Fascist Italy. She overcame incredible setbacks and was awarded the 1986 #NobelPrize in Physiology or Medicine. #WomeninScience

"A true mentor is someone who has more imagination about you than you have about yourself" nejm.org/doi/10.1056/NE…

Join the discussion with the experts in TB research. Date: 20th March 2024  Time: 11:45 am – 5:30 pm  Venue: Matrix Level 5,   30 Biopolis Street,   Codon A & B rooms,  Singapore 138671  Remarks: Lunch and refreshments are provided. To register click: shorturl.at/cfNX9

Proud to share our work out now in nature nature.com/articles/s4158…! In an amazing collaboration w/ Liz Campbell & Maddie Delbeau Darst-Campbell Lab we identify the/a source of the fitness cost of rifampicin resistance (RifR) in Mtb and how some compensatory mutations rescue the cost!

I am thrilled to share that I won Best Poster award at 3rd Annual Symposium on Innovations in Anti-mycobacterial Drug Discovery NTU Singapore. It was a pleasure to recieve this award from Prof. Peter Sander. Thank you Amit Singhal for guidance! A*STAR Infectious Diseases (ID) Labs #TB #Drugdiscovery

Had an amazing time at the 3rd Annual Symposium: Innovations in anti-mycobacterial Drug Discovery. Got to see some biggest brains in the world of NTM and TB - seriously these folks probably dream in molecular structures. Talks were fantastic@Thanks NTU Singapore

Great. "#Heterogenity" is the theme in TB symposium next year. We are organizing an EMBO, details coming soon Dhiraj kumar Priscille Brodin coming-soon.embo.org/gw25-02

3rd Annual Symposium: Innovations in anti-mycobacterial Drug Discovery ntu.edu.sg/ias/news-event…. Thank you! It was an awesome meeting.

Happy to share the research work from DBT-THSTI . This work, rdcu.be/dL6Ti was done by students Tannu, saurabh chugh. We have characterized menAT TA systems from Mtb. The work was funded by DBT/WT India Alliance. Collaborative work with Krishan Gopal Thakur, Amit Awasthi.

Science is a career full of rejection & self doubt. Most scientists don't go around collecting awards & kudos but sit there wondering if anyone reads our papers. Telling a scientist whose work you like that you value & appreciate what they do is a small & very meaningful gesture.

Thrilled to share that we have 2 new manuscripts on drug-resistant #tuberculosis out at Nature Communications ! In this pair of manuscripts, we investigated changes in #mtb physiology associated with INH resistance. 1/n nature.com/articles/s4146… nature.com/articles/s4146…

Would you prefer to lead a lab alone or together with a science buddy? How interesting would be a research institute where joint labs are the standard?!