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Looking forward to see this one when it is published formally, but for now enjoy some excellent prebiotic peptide bond chemistry

Another step forward in understanding the origins of proteins on Earth. Nice work guys! Saidul Islam @DrCallumFoden Matthew Powner

#MischiefMovieNight The Stinking Bishop award for Cheesiest Meet Cute

Excited to share the 1st paper from my PhD, online now in Angewandte Chemie! TNA nucleotides can form under the same conditions that give ribonucleotides. Our route selects for the correct threo-isomer using UV irradiation to remove the unwanted by-products: onlinelibrary.wiley.com/doi/10.1002/an…

pubs.acs.org/doi/10.1021/ja… Check it out in J. Am. Chem. Soc. - everything you need to know about photochemistry that could have been promoted by the Sun on the young Earth, making the molecules of life! The main text is more attractive than the TOC, I promise :) #prebioticchemistry #ool

Check out our @MRC_LMB latest work on the incredible prebiotic chemistry of #RNA 😁 We discovered a #prebiotic reaction that provides both RNA and #DNA purine nucleosides, RNA via an until-now unobserved radical sulfitylation mechanism pubs.acs.org/doi/full/10.10… #originoflife

I have a new chemistry PhD position starting in Oct. 2022. This is a great opportunity to work on the origins of life at King's College London. Please RT and share- it would be a big help to me! KCL Natural, Mathematical & Engineering Sciences ⁦FindAPhD⁩ #chemtwitter ⁦King's Chemistry⁩ findaphd.com/phds/project/o…

It has been a bit of long stretch since my last paper, but now here is our latest work currently ASAP in JACS. pubs.acs.org/doi/10.1021/ja… An alternative method of prebiotic aminoacylation via phosphoramidate chemistry.

It went live today :) Enzyme free aminoacylation of RNA via a phosphoramidate-ester intermediate pubs.acs.org/doi/pdf/10.102…

Just come out in JACS ASAP Chemistry to create loops in RNA under prebiotic conditions pubs.acs.org/doi/10.1021/ja… So pleased to contribute to this work. Well done Long-Fei Wu Liu Ziwei Szostak Lab

Template-Free Assembly of Functional RNAs by Loop-Closing Ligation @MRC_LMB Harvard Chemistry Harvard Medical School MassGeneral Medicine Harvard University #Template #Assembly #RNA #Loop #Closing #Ligation pubs.acs.org/doi/10.1021/ja…

Bohemian rhapsody for postdocs: Is this a real job? Or more like a PhD? Caught in short contracts No chance of stability Open your eyes Look up to PIs and see I'm just a postdoc I get no sympathy Because I'm easy come, easy go Stress is high Pay is low

Yay! Our most recent article (experiment+theory) about the photochemistry of a potentially prebiotic precursor to RNA nucleotides, 2-thiooxazole, has just been published in PCCP ! pubs.rsc.org/en/content/art… Matthew Powner Sam Roberts Lauren Bertram CHEM@PWr Politechnika Wrocławska

Do you want to know why Lysine is a privileged amino acid and about it’s late addition to the code!! here it goes Congratulations 🎉🎉and great work by ⁦Benji Thoma⁩ ⁦Matthew Powner⁩ ⁦Journal of the American College of Surgeons (JACS)⁩ pubs.acs.org/doi/10.1021/ja…

Our latest paper on Selective Synthesis of Lysine Peptides and the Prebiotically Plausible Synthesis of Catalytically Active Diaminopropionic Acid Peptide Nitriles in Water pubs.acs.org/doi/10.1021/ja… great work by Benji Thoma UCL Chemistry UCL J. Am. Chem. Soc.

Why are amino acids assigned to the codons they are? Would the earliest forms of translation needed the decoding centre of the ribosome? Find out in our new preprint biorxiv.org/content/10.110… Meng Su

A couple of weeks ago I had the pleasure of giving a talk as part of the PCE3 seminar series. It was livestreamed and you can find it on youtube youtube.com/watch?v=hE1LQq…

I'm pleased to say our work on codon:anticodon binding at the origins of life on Earth has just been put up online at JACS! pubs.acs.org/doi/10.1021/ja… Thanks Meng Su for including me :)