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Position available at Exeter Med School to work with on alternative splicing and epigenetic modifications in models of Alzheimer's disease pathology. Exeter Neuroscience jobs.exeter.ac.uk/hrpr_webrecrui… Please RT!

#DataScience #PhD opportunity for quantitative student looking to apply their skills to big biological datasets. Be part of the @GW4BioMedDTP Exeter Med School and Jonathan Mill exploring methods to computationally derive cell-type specific epigenetic profiles to understand

Excited to share that this work is now out in Scientific Reports 🥳Give it a read, download, share! nature.com/articles/s4159…

Congratulatuons Rebecca! And thanks so much to the panel, always a pleasure to talk about my work. Thanks to the PDA organisers for a great day of science 👨🏼‍🔬

1 in 3 names are missing on the #Lionesses shirts tonight, representing the 1 in 3 of us born in the UK today who will develop dementia. Tonight’s match was dedicated to Alzheimer's Society, raising vital funds to those devastated by dementia. Donate now: alzheimers.org.uk 👈

Some superb talks today around neuroinflammation in Alzheimer's Disease at #AAIC23 So don't miss out on the chance to come and chat all things iPSC microglia and CRISPR screening with me at poster 111 🧬🔬

Come hear Marta Pérez Alcántara presenting on how we're mapping sceQTLs in iPSC-derived microglia to interpret neurodegeneration GWAS variants. Starting soon: 11:45am Ballroom A. A collaboration with Open Targets #ASHG2023

Microglia NLRP3 inflammasome 'DUBbed' by UCH-L1 zhu liang Andreas Damianou Frederik Heymann Lassen Oxford Discovery Proteomics Tao Dong Group Ricardo A. Fernandes Ed Tate Centre for Medicines Discovery CAMS Oxford Institute Oxford Drug Discovery Institute Kennedy Institute of Rheumatology Big Data Institute Centre for Human Genetics Dunn_School (now @DunnSchool.bsky.social) Nuffield Department of Medicine biorxiv.org/content/10.110…

Excited to see this work from my Postdoc in Andrew Bassett's lab at Wellcome Sanger Institute finally out in the world! biorxiv.org/content/10.110… we found an AD-associated variant in PTK2B that actually has a causal effect on chromatin accessibility, gene expression and microglial function

If you are at #ADPD2024 in Lisbon come see our posters of our studies of DNA methylation meta-analyses in Lewy body disease led by Josh Harvey and Jennifer Imm, and spatial transcriptomics in the J20 amyloid model led by Millie Sander

Wednesday cellfie: KOLF2.1S iPSC microglial + neuron co-cultures, so pretty😍What's not shown is the pain of optimizing these conditions... Hopefully these models can help us further understand the molecular basis of Alzheimer's disease🧠 #ForACure

We're back in the studio today, recording a podcast with Alexi Nott 🏳️‍🌈 Josh Harvey Sarah Marzi Dr Sam Washer & hosted by Fiona McLean. Can you guess the topic?

👋 switching over to bsky, give me a follow for more microglial antics bsky.app/profile/swashe…