Deadline for the roscoff transcription and genome maintenance has been extended to may 21th!👇

Check out the latest work from the Steve Jackson Lab led by @cjcarnie et al!

SUMO/ubiquitin E3 ligase #TOPORS promotes #decitabine tolerance by removal of DNMT1-DNA crosslinks; while dCMP deaminase DCTD generates 5-aza-dUMP & exacerbates cytotoxicity indep. of DNA-protein crosslinks @cjcarnie et al @stingele_lab Steve Jackson Lab embopress.org/doi/full/10.10…

With 3 approved epigenetic drug classes and many more under clinical investigation, epigenetic targets are gaining traction. Here, we take survey of developments and hurdles in targeting the cancer epigenome. Thank you Nature Cancer for the opportunity nature.com/articles/s4301…

Worth reading !!

Two exciting opportunities for suitably qualified postgraduates/postdocs to join the Steve Jackson lab at the world renowned CRUK Cambridge Institute Cambridge University, jobs.cam.ac.uk/job/48675/ and jobs.cam.ac.uk/job/48762/. Come join us!

We are recruiting for a Research Assistant (Computing) (Fixed Term) Cambridge University jobs.cam.ac.uk/job/48960/ Please share

Now out in Genome Medicine BMC. Transform your #crispr screens with "Exorcise", EXOme-guided Re-annotation of nuCleotIde SEquences, doi.org/10.1186/s13073….

This exciting novel discovery, published in Nature Communications, with contributions from the Balasubramanian lab Cambridge Chemistry, was supported by Cancer Research UK, The Mark Foundation for Cancer Research, Wellcome and European Research Council (ERC).

Don't miss this opportunity to learn about #CRISPR from world experts including Thijn Brummelkamp The Netherlands Cancer Institute, @durocher1, Erika Alden DeBenedictis, @LeopoldParts Wellcome Sanger Institute and Weixin Tang UChicago Chemistry. Bursary application deadline 14 Jan, abstract deadline 4 Feb. Tell your friends!

Great opportunity and great mentor!

Excited to share our preprint, work spearheaded by PhD student Jordan Wilson with Marciniak Lab The CIMR, Villunger Lab & our European Research Council (ERC) partners Jacob Corn & Joanna Loizou. This sheds light on the action of WEE1 inhibitors and their therapeutic use, bit.ly/4bDpxZl

“To write for impact means to keep it as simple as possible.” Good read and very insightful. nature.com/articles/s4158…

A BIG STUDY in Nature Medicine: Which food makes you age faster? Scientists looked at 105,000 people in 30 years. The statistics is impressive. The study is open-access, so everyone can read it. 📍 Findings: The diet that ROCKS: fruits, vegetables, whole grains, unsaturated

Research Assistant (Jackson Group) (Fixed Term) Cambridge University jobs.cam.ac.uk/job/50998/

Thrilled and excited to share our latest work published in #BloodJournal. We uncover how defective neutrophil clearance drives #myelofibrosis via immune checkpoint #CD24 in myeloproliferative neoplasms. The First Edition⬇️ ashpublications.org/blood/article/…

8 Greatest Laws I know at 40, I wish I knew at 20: 1.