Samuel Kareff, MD, MPH (@samuelkareffmd) 's Twitter Profile
Samuel Kareff, MD, MPH

@samuelkareffmd

MedOnc/Heme @BHCancerCare +CHO #BocaRaton #DelrayBeach
Former #MedEd Chiefs @HemOncMiami + @gtown_medres
Tweets/likes ≠ medical advice | he/him | #LCSM | #GISM

ID: 1432716328230600705

linkhttps://www.linkedin.com/in/samuel-kareff-md-mph-50b07263/ calendar_today31-08-2021 14:47:41

1,1K Tweet

1,1K Followers

798 Following

Pashtoon Kasi MD, MS (@pashtoonkasi) 's Twitter Profile Photo

#GI25🎤drop #NEST🪺🙋🏻‍♂️🙌🏽 |➖➖➖➖➖➖➖➖➖➖ 💯 | | | | | | | | |————————————————— ✅NO RECURRENCES📅! 💡Neoadjuvant immunotherapy keeps delivering! 👉🏽Patients with MSS🧊NOT just MSI-High🔥colorectal #cancer. Goal is to👏🏾*CURE*👏🏾more patients. 🔜Phase2/3 OncoAlert ASCO

#GI25🎤drop #NEST🪺🙋🏻‍♂️🙌🏽

|➖➖➖➖➖➖➖➖➖➖ 💯 
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✅NO RECURRENCES📅! 

💡Neoadjuvant immunotherapy keeps delivering!

👉🏽Patients with MSS🧊NOT just MSI-High🔥colorectal #cancer.

Goal is to👏🏾*CURE*👏🏾more patients.

🔜Phase2/3
<a href="/OncoAlert/">OncoAlert</a> <a href="/ASCO/">ASCO</a>
Chinmay Jani (@jani_chinmay) 's Twitter Profile Photo

Read about our study on Healio! Thank you, Healio Pulmonology , for helping further spread awareness about risk factors driving #lungcancer mortality. While tobacco-related deaths decline, the impact of particulate matter continues to rise. Sylvester Comprehensive Cancer Center Miami Hem/Onc Program Director gilberto lopes

Stephen V Liu, MD (@stephenvliu) 's Twitter Profile Photo

Dr. Jordi Remon discusses uncommon #EGFR mutations in NSCLC at #ITCD2025. Afatinib approved here but osimertinib has some activity. Is using PACC a better approach to guiding therapies? Afatinib probably preferred for me in exon 18 but need to manage toxicity aggressively.

Dr. <a href="/JordiRemon/">Jordi Remon</a> discusses uncommon #EGFR mutations in NSCLC at #ITCD2025. Afatinib approved here but osimertinib has some activity. Is using PACC a better approach to guiding therapies? Afatinib probably preferred for me in exon 18 but need to manage toxicity aggressively.
Chinmay Jani (@jani_chinmay) 's Twitter Profile Photo

Grateful to @ascopost for featuring our article! Our momentum in tackling #tobacco-associated lung cancer must continue, but we also need to raise awareness and deepen our research on #airpollution and other risk factors related cancer. ASCO IASLC gilberto lopes Dr. Estela Rodriguez

Jarushka Naidoo (@drjnaidoo) 's Twitter Profile Photo

Ph Ib Trial Ivonescimab (PD-1/VEGF bispecific)+Plt/Etop in 1L ES SCLC JTO & JTO CRR: - Ivo (3 dose levels)+plt/etopx4 ➡️ivo maintenance - 35pts, ORR 80%, DCR 91% - g3+ TRAEs 60% (⬇️ANC, WBC, Hb) Intriguing. VEGF not a traditional sclc target OncoAlert #LCSM jto.org/article/S1556-…

Eric K. Singhi, MD (@lungoncdoc) 's Twitter Profile Photo

The slide we have all been waiting for: OS in #MARIPOSA ▫️OS was significantly improved with amivantamab + lazertinib (HR 0.75) ▫️3 yr OS: 60% with amivantamab + lazertinib v 51% for osimertinib ▫️Curves appear to widen over time Oncology Brothers OncoAlert

The slide we have all been waiting for: OS in #MARIPOSA 

▫️OS was significantly improved with amivantamab + lazertinib (HR 0.75)
▫️3 yr OS: 60% with amivantamab + lazertinib v 51% for osimertinib
▫️Curves appear to widen over time 

<a href="/OncBrothers/">Oncology Brothers</a> <a href="/OncoAlert/">OncoAlert</a>
Baptist Health Cancer Care (@bhcancercare) 's Twitter Profile Photo

We’re thrilled to welcome three new specialists to Baptist Health #LynnCancerInstitute: 🔹 Dr. Christine Pestana 🔹 Dr. Ross Taylor 🔹 Dr. Samuel Kareff These experts will help us provide cutting-edge cancer care. Learn more: BaptistHealth.net/LCI

We’re thrilled to welcome three new specialists to Baptist Health #LynnCancerInstitute:
🔹 Dr. Christine Pestana
🔹 Dr. Ross Taylor
🔹 Dr. Samuel Kareff
These experts will help us provide cutting-edge cancer care. Learn more: BaptistHealth.net/LCI
gilberto lopes (@glopesmd) 's Twitter Profile Photo

And the fun starts! From @asco #asco25 press release Overall survival was 30.3 months in the encorafenib/cetuximab with mFOLFOX6 arm, 19.5 months in the encorafenib/cetuximab alone arm, and 15.1 months in the control arm. PFS pic below NEJM asco.org/about-asco/pre…

And the fun starts! 
From @asco #asco25 press release 

Overall survival was 30.3 months in the encorafenib/cetuximab with mFOLFOX6 arm, 19.5 months in the encorafenib/cetuximab alone arm, and 15.1 months in the control arm.

PFS pic below <a href="/NEJM/">NEJM</a> 

asco.org/about-asco/pre…
gilberto lopes (@glopesmd) 's Twitter Profile Photo

Alcohol and cancer in the US From Chinmay Jani @asco #asco25 Key Takeaway Points •Alcohol-associated cancer deaths have doubled in the USA •Disproportionate burden: Males and the 55+ age group. •Despite reduction in absolute mortality rates in some groups, proportional

Alcohol and cancer in the US 

From <a href="/Jani_Chinmay/">Chinmay Jani</a> @asco #asco25 

Key Takeaway Points

•Alcohol-associated cancer deaths have doubled in the USA
•Disproportionate burden: Males and the 55+ age group.
•Despite reduction in absolute mortality rates in some groups, proportional
Chinmay Jani (@jani_chinmay) 's Twitter Profile Photo

This morning, I had the honor of presenting my first Rapid Oral at #ASCO25 🎤 — a truly unforgettable experience ✨. Our study highlights the rising burden of #alcohol-associated cancers 🍷🎗️ across sites, age groups, and sexes gilberto lopes Dr. Estela Rodriguez . Grateful to all my mentors

This morning, I had the honor of presenting my first Rapid Oral at #ASCO25 🎤 — a truly unforgettable experience ✨. Our study highlights the rising burden of #alcohol-associated cancers 🍷🎗️ across sites, age groups, and sexes <a href="/GlopesMd/">gilberto lopes</a> <a href="/Latinamd/">Dr. Estela Rodriguez</a> . Grateful to all my mentors
NEJM (@nejm) 's Twitter Profile Photo

Presented at #ASCO25: A 3-year structured exercise program after adjuvant chemotherapy for colon cancer improved disease-free and overall survival, physical functioning, and fitness, as compared with health education alone. Full CHALLENGE phase 3 trial results:

Presented at #ASCO25: 

A 3-year structured exercise program after adjuvant chemotherapy for colon cancer improved disease-free and overall survival, physical functioning, and fitness, as compared with health education alone. Full CHALLENGE phase 3 trial results:
gilberto lopes (@glopesmd) 's Twitter Profile Photo

And of course: Lung Oral session @asco #asco25 #lcsm My take so far: Krystal 7 IO + adagrasib is interesting as it was tolerated, but efficacy does not seem to be better than with IO alone or with chemo. Will need to wait for and see randomized trial Dato shows interesting

And of course: Lung Oral session

@asco #asco25 #lcsm 

My take so far:

Krystal 7 IO + adagrasib is interesting as it was tolerated, but efficacy does not seem to be better than with IO alone or with chemo. Will need to wait for and see randomized trial 

Dato shows interesting
Jennifer A. Marks, MD (@jennifermarksmd) 's Twitter Profile Photo

Dr. Rafeh Naqash, MD walks us through DeLLphi-301 and ongoing BiTEs targeting #DLL3 . 🧠With tarlatamab, we cannot forget that ICANS can occur much later than what we see in heme malignancies 🧠ASCO #ASCO25 #lcsm #lcam #SCLC

Dr. <a href="/thenasheffect/">Rafeh Naqash, MD</a> walks us through DeLLphi-301 and ongoing BiTEs targeting #DLL3 . 
🧠With tarlatamab, we cannot forget that ICANS can occur much later than what we see in heme malignancies 🧠<a href="/ASCO/">ASCO</a> #ASCO25 #lcsm #lcam #SCLC
Chul Kim (@chulkimmd) 's Twitter Profile Photo

Lurbinectedin + atezolizumab in 2L SCLC (an IIT 👏 ) shows: - ORR 40.4% (IO naive: 44.1%, IO experienced: 37.3%). Intriguing question regarding synergy. - mPFS 4.6 mo, mOS 10.1 mo - Sets the stage for IMforte phase III (to be presented during #ASCO25)

Lurbinectedin + atezolizumab in 2L SCLC (an IIT 👏 ) shows:
- ORR 40.4% (IO naive: 44.1%, IO experienced: 37.3%). Intriguing question regarding synergy.
- mPFS 4.6 mo, mOS 10.1 mo
- Sets the stage for IMforte phase III (to be presented during #ASCO25)