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Hi all, we have another lab member starting a twitter account this week - please follow PhD candidate Sanjna Singh Sanjna Singh, who is researching efferocytosis (how cells clean up dead cell bodies), which is really important for #Alzheimers #dementia SAHMRI Uni of Adelaide

Join us for our next Alzheimer's Association and WIA Journal Club joint session on Tuesday April, 19th 4:30 - 5:00 PM EST (US and Canada). Register at bit.ly/0419JC #WomenInScience #WomenInSTEM Alzheimer's Association Sanjna Singh

Excited to share that some of my PhD work is now online CDD press rdcu.be/dE0MP We developed a reporter to track the acidification of dead cells by phagocytes. Huge thanks to my supervisors Assoc. Prof. Tim Sargeant Ville Makinen and all co-authors Julien Bensalem Aaron Casey

Excited to share our new preprint - a high #protein meal after an overnight #fast does NOT change autophagy in people… this was a really surprising result for us! The question remains: how can we alter #autophagy in a person? 👥 SAHMRI Assoc. Prof. Tim Sargeant medrxiv.org/content/10.110…

📢📢New work from Dr Linh Dang in my group - analysis of physiological human autophagic flux in leukocytes. Surprises related to ageing, sex effects, and nutrient sensing! SAHMRI #autophagy #aging Cell-type specific autophagy in human leukocytes biorxiv.org/content/10.110…

Check out our latest Comment in Nature Cell Biology on #autophagy (how cells of your body recycle damaged material). While declining autophagy is often seen as a hallmark of #ageing, we explore emerging exceptions to this idea. SAHMRI Uni of Adelaide nature.com/articles/s4155…

Does autophagy really decline with ageing? What can LC3-based measurements truly tell us about autophagy? And how can we bridge the gap between preclinical findings and human biology? We explore these questions in our latest comment in Nature Cell Biology: bit.ly/4cjOSHU

In our recent Nature Cell Biology comment, we highlight mounting evidence that —contrary to dogma— #autophagy doesn’t always decline with age.. in fact, it often increases! Sanjna Singh Assoc. Prof. Tim Sargeant SAHMRI The Hospital Research Foundation Group nature.com/articles/s4155…

New study: we measured autophagic flux in human blood and compare intermittent fasting with calorie restriction = the largest human autophagy study to date. Although significant, changes in autophagy were modest. #autophagy #fasting #aging SAHMRI physoc.onlinelibrary.wiley.com/doi/10.1113/JP…

In a recent study published by our group, we measured autophagic flux in human PBMCs. We cannot yet measure #autophagy in organs, which is why we are developing tissue specific autophagy biomarkers.

Our paper about how autophagy changes in mice as they age is now available at PLOS One ! Big thanks to Assoc. Prof. Tim Sargeant , Brad Turner & team, as well as SAHMRI , @uniofadelaide & The Hospital Research Foundation Group ! journals.plos.org/plosone/articl…

New research paper on human #autophagy from our group at SAHMRI. Dr Linh Dang analysed autophagic flux with cell type specificity. We show data important for designing clinical trials for human autophagy - cell type matters: faseb.onlinelibrary.wiley.com/doi/10.1096/fj… #aging