When cellular reprogramming meets AI: towards de novo cell design | Nature Reviews Genetics nature.com/articles/s4157…

Reconstructing Waddington's Landscape from Data biorxiv.org/content/10.110… conceptually cool- I will have to take your word for it when it comes to the maths

NewPreprint alert 📢 Thrilled to share our new work: A molecular cell atlas of endocrine signalling in human neural organoids 📄 Paper: [biorxiv.org/content/10.110…] 💻 Github: [github.com/GiuseppeTestaL…] Eager to know more? 👉🧵 1/

androgen (AND), estrogen (EST), glucocorticoid (GC), thyroid (THY), retinoic acid (RA), liver X (LX), and aryl hydrocarbon (AH) /7

establishing a living atlas to ground an iterative process of continuous refinement by the scientific community. Neural Organoid Hormonal Atlas (NOHA) Explore it here 💻[github.com/GiuseppeTestaL…] /16

🚀 Join us in Kyoto! ASHBi Symposium “Human Early Development in vivo and in vitro” 📅 Sep 18–19, 2025 | Kyoto University 🔍 14 experts share the latest in developmental biology & stem cell research 🔗 Register: forms.gle/hi917Zajb4frGP… 🌐 Info: ashbi.kyoto-u.ac.jp/event/event-sy…

[Research update!] ASHBi researchers discovered new '3D Genome Organizer' linked to fertility and cancer. NatureStructMolBiol check here more: doi.org/10.1038/s41594… Press release: ashbi.kyoto-u.ac.jp/ja/news_resear…

25th Anniversary of the FANTOM Meeting! 🎉 On this day 25 years ago (Aug 28, 2000), the 1st FANTOM meeting was held at the RIKEN Tsukuba Campus. For about two weeks, invited experts from Japan and abroad discussed and annotated 21,076 mouse full-length cDNAs. #FANTOM

🚀 Amazing experience in Zurich at Epigenetic Inheritance Symposium 2025! I presented my Master's thesis poster and met researchers who are shaping this fascinating field. Huge thanks to the organizers and to Giuseppe Testa & Sarah Stucchi for the support! #EIS25 #Epigenetics

Saitou, M., Nagano, M. & Mizuta, K. Mechanisms of human germ cell development. Nat Rev Mol Cell Biol (2025). doi.org/10.1038/s41580…

Wonderful to see our paper on the #organelle signatures of #neurons and #astrocytes out in final form - congratulations Shannon Rhoads and team! 🎉doi.org/10.1016/j.celr…

Sex cells made from scratch could revolutionize human reproduction go.nature.com/43eR7ch

BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 It started from my frustration with the depressing effect that the current publishing system has

In 1992 Peter Ratcliffe received this rejection letter from Nature. His findings were not "a sufficient advance in our understanding". 27 years later he won the Nobel Prize for the same discovery. Don't lose faith in the things you believe in.

Selective RNA sequestration in biomolecular condensates directs cell fate transitions go.nature.com/3X215du

CytoTRACE 2: an interpretable deep-learning method that uses scRNA-seq data to predict absolute developmental potential across datasets. nature.com/articles/s4159…

🐸 Xenopus laevis 💚 The frog that shaped modern developmental biology! ✨ Xenopus embryos have revealed how the body axis forms, cells choose their fate, and tissues self-organize during early development 📹 Video by Bioquest Sudio and Xenbase #ModelMonday #DevBio

The idea is to decouple the journals from the review step. They’ll still exist, but they’ll need to add other value. They’ll highlight, curate, add new perspectives. If they do a good job they can still be prestigious (like Scientific American or Wired). You’ll be proud that your

Today in nature we report a new prime editing strategy that can rescue a common cause of many genetic diseases in a disease-agnostic manner. This approach converts a redundant endogenous tRNA into an optimized suppressor tRNA, enabling a single prime edit to rescue premature